An H3 lysine 9 acetylation specific antibody is provided. In good agreement with the localization of its target acetylation, H3K9ac antibody was enriched in euchromatin, and its kinetics measurably changed upon treatment with a histone deacetylase inhibitor.
Figure 1 Specific binding of scFv (H3K9ac) to H3K9ac
The binding kinetics of scFv (H3K9ac) to peptides harboring H3K9ac and H3K9me2 were measured by surface plasmon resonance. The binding dissociation constants (KD; M) to H3K9ac at 25uC were shown.
Sato, Y., Mukai, M., Ueda, J., Muraki, M., Stasevich, T. J., Horikoshi, N., Kujirai, T., Kita, H., Kimura, T., Hira, S., Okada, Y., Hayashi-Takanaka, Y., Obuse, C., Kurumizaka, H., Kawahara, A., Yamagata, K., Nozaki, N., & Kimura, H. (2013). Genetically encoded system to track histone modification in vivo. Scientific reports, 3, 2436.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0146YC | Mouse Anti-H3K9ac Recombinant Antibody (clone v1) | IF | Mouse IgG |
FAMAB-0148YC | Mouse Anti-H3K9ac Recombinant Antibody (clone v3) | IF | Mouse IgG |
VS-0623-WK91 | Mouse Anti-H3K9ac Recombinant Antibody (clone scFv-58F) | ELISA, DB, WB, IF, IP, FuncS | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0146-YC-S(P) | Mouse Anti-H3K9ac Recombinant Antibody (clone v1); scFv Fragment | IF | Mouse scFv |
FAMAB-0147-YC-S(P) | Mouse Anti-H3K9ac Recombinant Antibody (clone v2); scFv Fragment | IF | Mouse scFv |
FAMAB-0148-YC-S(P) | Mouse Anti-H3K9ac Recombinant Antibody (clone v3); scFv Fragment | IF | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0146-YC-F(E) | Mouse Anti-H3K9ac Recombinant Antibody (clone v1); Fab Fragment | IF | Mouse Fab |
FAMAB-0147-YC-F(E) | Mouse Anti-H3K9ac Recombinant Antibody (clone v2); Fab Fragment | IF | Mouse Fab |
FAMAB-0148-YC-F(E) | Mouse Anti-H3K9ac Recombinant Antibody (clone v3); Fab Fragment | IF | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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