Human Anti-HCMV gB Recombinant Antibody (clone SM1-6) (CAT#: FAMAB-0145JF)
Recombinant monoclonal antibody specially binds to domain II of glycoprotein B (gB) of human cytomegalovirus (HCMV). This human anti-gB antibody (SM1-6) could be useful as biologicals in therapy of HCMV infections.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 Neutralization capacity of Dom I- and Dom II-specific mabs.
Human umbilical cord endothelial cells (HUVEC) and human retinal pigment epithelial cells (ARPE) were infected with the HCMV strain TB40E.
Pötzsch, S., Spindler, N., Wiegers, A. K., Fisch, T., Rücker, P., Sticht, H., ... & Winkler, T. H. (2011). B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies. PLoS pathogens, 7(8), e1002172.
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- HCMV gB
- Species Reactivity
- HCMV
- Clone
- SM1-6
- Applications
- WB, ELISA, FuncS
- Related Disease
- HCMV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Human Cytomegalovirus; HCMV; Human Cytomegalovirus envelope glycoprotein B; HCMV gB
- Gene ID
- 3077424
- UniProt ID
- F5HB53
- Function
- Neutralization
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-443-F(E) | Recombinant Anti-HCMV GB Antibody Fab Fragment | WB, IF, FuncS | Fab |
| MHH-443-F(E) | Recombinant Human Anti-HCMV GB Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| FAMAB-0173CQ-F(E) | Recombinant Mouse Anti-HCMV gB Antibody Fab Fragment (7-17) | ELISA, Neut | Mouse Fab |
| FAMAB-0142JF-F(E) | Human Anti-HCMV gB Recombinant Antibody (clone SM10); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0143JF-F(E) | Human Anti-HCMV gB Recombinant Antibody (clone 1G2); Fab Fragment | WB, ELISA, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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