Recombinant monoclonal antibody specially binds to domain II of glycoprotein B (gB) of human cytomegalovirus (HCMV). This human anti-gB antibody (SM1-6) could be useful as biologicals in therapy of HCMV infections.
Figure 1 Neutralization capacity of Dom I- and Dom II-specific mabs.
Human umbilical cord endothelial cells (HUVEC) and human retinal pigment epithelial cells (ARPE) were infected with the HCMV strain TB40E.
Pötzsch, S., Spindler, N., Wiegers, A. K., Fisch, T., Rücker, P., Sticht, H., ... & Winkler, T. H. (2011). B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies. PLoS pathogens, 7(8), e1002172.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-443-F(E) | Recombinant Anti-HCMV GB Antibody Fab Fragment | WB, IF, FuncS | Fab |
MHH-443-F(E) | Recombinant Human Anti-HCMV GB Antibody Fab Fragment | WB, Neut, FuncS | Fab |
FAMAB-0173CQ-F(E) | Recombinant Mouse Anti-HCMV gB Antibody Fab Fragment (7-17) | ELISA, Neut | Mouse Fab |
HPAB-0639-CN-F(E) | Recombinant Human Anti-HCMV gB Antibody Fab Fragment (2F10) | ELISA, Neut | Human Fab |
HPAB-0640-CN-F(E) | Recombinant Human Anti-HCMV gB Antibody Fab Fragment (2M16) | ELISA, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1032LC | Anti-HCMV gB Recombinant Antibody (TI-23) | ELISA | Humanized antibody |
MRO-1032LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (TI-23) | ELISA | Humanized antibody |
MRO-1032LC-F(E) | Anti-HCMV gB Recombinant Antibody Fab Fragment (TI-23) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1033LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C1) | ELISA | Human antibody |
MRO-1034LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C3) | ELISA | Human antibody |
MRO-1035LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C4) | ELISA | Human antibody |
MRO-1036LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C7) | ELISA | Human antibody |
MRO-1037LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C23) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-1438LC | Recombinant Human Anti-HCMV gB Antibody (MAb C23) | WB | IgG1 |
EPAF-1497LC | Recombinant Mouse Anti-HCMV gB Antibody (CH28-2) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0639-CN | Recombinant Human Anti-HCMV gB Antibody (2F10) | ELISA, Neut | Human IgG |
HPAB-0640-CN | Recombinant Human Anti-HCMV gB Antibody (2M16) | ELISA, Neut | Human IgG |
HPAB-0641-CN | Recombinant Human Anti-HCMV gB Antibody (2N9) | ELISA, Neut | Human IgG |
HPAB-0642-CN | Recombinant Human Anti-HCMV gB Antibody (4P12) | ELISA, Neut | Human IgG |
HPAB-0643-CN | Recombinant Human Anti-HCMV gB Antibody (5P9) | ELISA, Neut | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0639-CN-S(P) | Recombinant Human Anti-HCMV gB Antibody scFv Fragment (2F10) | ELISA, Neut | Human scFv |
HPAB-0640-CN-S(P) | Recombinant Human Anti-HCMV gB Antibody scFv Fragment (2M16) | ELISA, Neut | Human scFv |
HPAB-0641-CN-S(P) | Recombinant Human Anti-HCMV gB Antibody scFv Fragment (2N9) | ELISA, Neut | Human scFv |
FAMAB-0144JF-S(P) | Human Anti-HCMV gB Recombinant Antibody (clone 2C2); scFv Fragment | WB, ELISA, FuncS | Human scFv |
FAMAB-0145JF-S(P) | Human Anti-HCMV gB Recombinant Antibody (clone SM1-6); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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