Mouse Anti-HCV Core Protein Recombinant Antibody (clone 2G3) (CAT#: FAMAB-0302JF)

Recombinant monoclonal antibody specially binds to HCV core. 2G3 is a mouse monoclonal antibody that can be potentially used in the treament of pateints with HCV infection.


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WB

Figure 1 Immunoprecipitation of HCV core protein from transformed REF cells.

Figure 1 Immunoprecipitation of HCV core protein from transformed REF cells.

Cells cotransfected with HCV core gene- and H-ras (A)- or c-myc (B)- transformed REF cells were labeled with [35S]methionine-cysteine.

Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.

IF

Figure 2 Indirect immunofluorescence using transformed REF cells.

Figure 2 Indirect immunofluorescence using transformed REF cells.

Cells cotransfected with HCV core and c-myc genes and cells recovered from tumors generated by inoculation of HCV core gene.

Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.

ELISA

Figure 3 Comparison of the growth rates of REF cells transformed by cotransfection with HCV core and c-myc or H-ras genes.

Figure 3 Comparison of the growth rates of REF cells transformed by cotransfection with HCV core and c-myc or H-ras genes.

All results are representative of at least four independent experiments.

Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.


Specifications

  • Immunogen
  • Core expressed by bacteria
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • HCV core
  • Species Reactivity
  • HCV
  • Clone
  • 2G3
  • Applications
  • WB, ELISA, IF
  • Related Disease
  • HCV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HCV Core Protein antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunofluorescence.

Target

  • Alternative Names
  • Hepatitis C virus; HCV; Hepatitis C virus core protein; HCV core protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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