Recombinant Anti-HGFAC Eliminating Antibody, pH-Sensitive (Fab40. deltaTrp var.)
CAT#: VS-0625-YC142
The anti-HGFAC eliminating antibody is an engineered pH-sensitive antibody against human HGFAC. HGFAC is a protease converting HGF to its active form, influenced by alternative splicing. The antibody has a novel HGFAC-sweeping activity in vivo, which selectively eliminatesthe soluble HGFAC from plasma. Compared to conventional antibody, the mAb exerted in vivo efficacy by simultaneously engineering both pH-dependent antigen binding, to mimic the pH-dependent receptor-ligand binding of such endocytic receptors, and increased FcRn binding affinity at neutral pH, to mimic the cell-bound form of the receptors.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109758-HGFAC
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Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human HGFAC
- Species Reactivity
- Human
- Clone
- Fab40. deltaTrp var.
- Applications
- Antigen-Sweeping In Vivo.
Product Property
- Purification
- Protein A/G purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS only
- Preservative
- None
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-463 | Recombinant Anti-human HGFAC Antibody | WB, ELISA, IHC, FuncS | IgG |
| MHH-463 | Recombinant Human Anti-human HGFAC Antibody | Neut, WB, FuncS | IgG |
| PABL-133 | Recombinant Human Anti-HGFAC Antibody (Ab40) | WB, ELISA, FuncS | IgG |
| HPAB-S0059-YC | Human Anti-HGFAC Recombinant Antibody (clone Ab39) | ELISA | Human IgG1 |
| HPAB-S0060-YC | Human Anti-HGFAC Recombinant Antibody (clone Ab40) | ELISA, Inhib | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-463-F(E) | Recombinant Anti-human HGFAC Antibody Fab Fragment | FC, WB, FuncS | Fab |
| PFBL-133 | Recombinant Human Anti-HGFAC Antibody Fab Fragment (Ab40) | WB, ELISA, FuncS | Fab |
| PFBZ-058 | Human Anti-HGFAC Recombinant Antibody (clone Ab58); Fab Fragment | ELISA, Block | Human Fab |
| HPAB-S0059-YC-F(E) | Human Anti-HGFAC Recombinant Antibody (clone Ab39); Fab Fragment | ELISA | Human Fab |
| HPAB-S0060-YC-F(E) | Human Anti-HGFAC Recombinant Antibody (clone Ab40); Fab Fragment | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-463-S(P) | Recombinant Anti-human HGFAC Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| PSBL-133 | Recombinant Human Anti-HGFAC Antibody scFv Fragment (Ab40) | WB, ELISA, FuncS | scFv |
| PSBZ-058 | Human Anti-HGFAC Recombinant Antibody (clone Ab58); scFv Fragment | ELISA, Block | Human scFv |
| PSBW-058 | Human Anti-HGFAC Recombinant Antibody (clone Ab75); scFv Fragment | ELISA, Block | Human scFv |
| HPAB-S0059-YC-S(P) | Human Anti-HGFAC Recombinant Antibody (clone Ab39); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-079CT | Human Anti-HGFAC Recombinant Antibody (TAB-079CT) | ELISA | Humanized antibody |
| TAB-079CT-S(P) | Human Anti-HGFAC Recombinant Antibody; scFv Fragment (TAB-079CT-S(P)) | ELISA | Humanized scFv |
| TAB-079CT-F(E) | Human Anti-HGFAC Recombinant Antibody; Fab Fragment (TAB-079CT-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-083 | Recombinant Human Anti-HGFA Antibody (Fab40.deltaTrp) | WB, ELISA, Neut, FuncS | IgG |
| PABX-083-S (P) | Recombinant Human Anti-HGFA Antibody scFv Fragment (Fab40.deltaTrp) | WB, ELISA, Neut, FuncS | scFv |
| PABX-083-F (E) | Recombinant Human Anti-HGFA Antibody Fab Fragment (Fab40.deltaTrp) | WB, ELISA, Neut, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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