AbPlus™ Anti-HRAS Magnetic Beads (VS-0724-YC1294)
CAT#: VS-0724-YC1294
The AbPlus Anti-HRAS Magnetic Beads (VS-0724-YC1294) is an innovative affinity resin which is bound with anti-HRAS specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of HRAS protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70222/1357_B12_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2015/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49830/118215_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49830/118215_A_8_3.jpg
Normal Tissue
Figure 5 Gallbladder
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49830/118215_A_5_4.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49830/118215_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174775-HRAS
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-HRAS specific antibody
- Target
- HRAS
- Immunogen
- Recombinant human HRAS, aa 1-186.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Alternative Names
- HRas Proto-Oncogene, GTPase; V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog; Harvey Rat Sarcoma Viral Oncogene Homolog; Transforming Protein P21; C-H-RAS; P21ras; HRAS1; Ras Family Small GTP Binding Protein H-Ras; Harvey Rat Sarcoma Viral Oncoprotein; Transformation Gene: Oncogene HAMSV; GTP- And GDP-Binding Peptide B; C-Ras-Ki-2 Activated Oncogene; Ha-Ras1 Proto-Oncoprotein;
- Gene ID
- 3265
- UniProt ID
- P01112
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Related Diseases
Bladder Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "HRAS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1684z | Mouse Anti-HRAS Recombinant Antibody (clone 2H12) | WB, IF, IHC | Mouse IgG1 |
| PABZ-074 | Human Anti-HRAS Recombinant Antibody (clone YC106) | WB, IHC, IF, FuncS | Human IgG |
| MOB-2323CT | Recombinant Mouse anti-Human HRAS Monoclonal antibody (UN60) | WB, ELISA | |
| HPAB-0159-YJ | Mouse Anti-HRAS Recombinant Antibody (clone CBH03YJ) | ELISA, ICC, FuncS | Mouse IgG |
| FAMAB-1496CQ | Human Anti-HRAS Recombinant Antibody (clone Y13-238) | IP | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-074 | Human Anti-HRAS Recombinant Antibody (clone YC106); Fab Fragment | WB, IHC, IF, FuncS | Human Fab |
| HPAB-0159-YJ-F(E) | Mouse Anti-HRAS Recombinant Antibody (clone CBH03YJ); Fab Fragment | ELISA, ICC, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-074 | Human Anti-HRAS Recombinant Antibody (clone YC106); scFv Fragment | WB, IHC, IF, FuncS | Human scFv |
| HPAB-0159-YJ-S(P) | Mouse Anti-HRAS Recombinant Antibody (clone CBH03YJ); scFv Fragment | ELISA, ICC, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0260MZ | Chicken Anti-HRAS Polyclonal IgY | WB | Chicken antibody |
| BRD-1076MZ | Chicken Anti-H-Ras Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-913CQ | Rat Anti-HRAS Recombinant Antibody (clone Y13-259) | WB, ICC, IF, IP, IHC-P, Neut, IHC-Fr | Rat IgG1, κ |
| NEUT-914CQ | Rat Anti-HRAS Recombinant Antibody (clone CBL947) | IF, IHC, IP, Neut, WB | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1674 | Rabbit Anti-HRAS Recombinant Antibody (clone DS1674AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1058 | Anti-HRAS Immunohistochemistry Kit | IHC | |
| VS-0525-XY3280 | Anti-Mouse HRAS Immunohistochemistry Kit | IHC | |
| VS-0525-XY3279 | Anti-Human HRAS Immunohistochemistry Kit | IHC | |
| VS-0525-XY3281 | Anti-Canine HRAS Immunohistochemistry Kit | IHC |
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