Rabbit Anti-HRH3 Recombinant Antibody (clone R04-3I4)

CAT#: VS3-FY1742

This R04-3I4 recombinant monoclonal antibody specifically binds to human HRH3. It cross-reacts with mouse, rat. The antibody has the positive detection of HRH3 protein by western blot analysis of HRH3/Histamine 3 Receptor in K562, C6, 3T3 lysates.

Gene Expression Tested Data
Figure 1 RNA cell line category: Cell line enriched (SCLC-21H)
Figure 1 Anti-HRH3 Antibody (VS3-FY1742) in WB.

Specifications

  • Immunogen
  • Synthetic peptide of human HRH3/histamine 3 receptor
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat HRH3
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R04-3I4
  • Applications
  • Western Blot
  • MW
  • The calculated weight of the target protein is approximately 49 kDa, while the observed molecular weight stands at 49 kDa.
  • Related Disease
  • Central Nervous System Disease and Spontaneous Ocular Nystagmus

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Histamine Receptor H3; GPCR97; HH3R; H3R; G Protein-Coupled Receptor 97; G-Protein Coupled Receptor 97; Histamine H3 Receptor
  • Sequence Similarities
  • Belongs to the G-protein coupled receptor 1 family.
  • Post Translation Modifications
  • Disulfide bond
    Glycoprotein
    Phosphoprotein
  • Function
  • The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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Isotype Control

Secondary Antibody

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