AbPlus™ Anti-HSPB1 Magnetic Beads (VS-0724-YC1360) (CAT#: VS-0724-YC1360)
The AbPlus Anti-HSPB1 Magnetic Beads (VS-0724-YC1360) is an innovative affinity resin which is bound with anti-HSPB1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of HSPB1 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47330/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47330/if_selected.jpg

Figure 2 Esophagus
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4439/17421_B_4_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4439/17421_B_4_1_val_selected.jpg

Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_A_9_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_A_9_3.jpg

Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_A_7_5.jpg

Figure 5 High expression in vagina
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_B_2_2.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47331/104843_B_2_2.jpg

Figure 6 RNA cell line category: Cell line enhanced (hTCEpi, MCF7)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106211-HSPB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106211-HSPB1
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-HSPB1 specific antibody
- Target
- HSPB1
- Immunogen
- Recombinant human HSP27, aa 1-205.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
- Alternative Names
- Heat Shock Protein Family B (Small) Member 1; Estrogen-Regulated 24 KDa Protein; Stress-Responsive Protein 27; Heat Shock 27kDa Protein 1; Heat Shock 27kD Protein 1; Heat Shock 27 KDa Protein; 28 KDa Heat Shock Protein; HSP27; HSP28; SRP27;
- Gene ID
- 3315
- UniProt ID
- P04792
Downloads
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CAT | Product Name | Application | Type |
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MOB-0125MZ | Recombinant Mouse Anti-Heat Shock Protein-25 and Heat Shock Protein 27 Antibody (clone ISP25-19) | ELISA, WB, IF, IP | Mouse antibody |
MRO-0773-CN | Mouse Anti-HSPB1 Recombinant Antibody (clone 10-8) | WB, IF, IHC | Mouse IgG2b |
MRO-0774-CN | Rabbit Anti-HSPB1 Recombinant Antibody (clone CBACN-288) | WB, IF, IHC, IP, FC | Rabbit IgG |
VS3-CJ377 | Mouse Anti-HSPB1 Recombinant Antibody (VS3-CJ377) | WB, IHC | |
VS3-CJ378 | Rabbit Anti-HSPB1 Recombinant Antibody (VS3-CJ378) | WB, IHC, ICC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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