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    Mouse Anti-IDH2 Recombinant Antibody (clone 3E8D12) (CAT#: VS7-0425-WR114)

    This product is a mouse IgG1 recombinant antibody that binds to human IDH2. The antibody 3E8D12 recognizes a specific amino acid domain of human IDH2 (AA: 1-143). It can be used for IHC and FC assays.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/if_selected.jpg
    Normal Tissue
    Figure 2 Lymph node
    Figure 2 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_A_8_8.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_A_7_3.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_A_6_6.jpg
    Figure 7 Heart muscle
    Figure 7 Heart muscle
    (Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7831/21125_B_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (MOLT-4)
    Figure 8 RNA cell line category: Cell line enhanced (MOLT-4)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182054-IDH2

    Specifications

    • Immunogen
    • Recombinant human IDH2 (AA: 1-143) fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human IDH2
    • Species Reactivity
    • Human
    • Clone
    • 3E8D12
    • Molecule Class
    • Metabolic Enzyme
    • Applications
    • IHC, FC
    • Conjugate
    • Unconjugated
    • Related Disease
    • D-2-hydroxyglutaric aciduria 2 (D2HGA2); Glioma (GLM)

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • 0.05% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry-Paraffin: 1:200 - 1:1000
      Enzyme-linked Immunosorbent Assay: 1:10000
      Flow Cytometry: 1:200 - 1:400

    Target

    • Alternative Names
    • IDH; IDP; IDHM; IDPM; ICD-M; IDH-2; D2HGA2; mNADP-IDH
    • Long Name
    • Isocitrate Dehydrogenase (Nadp(+)) 2
    • Cellular Localization
    • Mitochondrion
    • Post Translation Modifications
    • Acetylation
    • Function
    • Oxidoreductase

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "IDH2"

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    IgG Antibody Products Rabbit Monoclonal Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-2317MZ Recombinant Mouse Anti-Human IDH2 Antibody ICC/IF, IHC-P, WB Mouse antibody
    MRO-0810-CN Rabbit Anti-IDH2 Recombinant Antibody (clone JA55-31) WB, IHC, FC Rabbit IgG
    VS-0923-FY102 Recombinant Mouse Anti-IDH2 Antibody (VS-0923-FY102) ELISA, WB Mouse IgG1
    VS-0724-YC13 Human Anti-IDH2 Recombinant Antibody (clone 2Q1) ELISA, FC Human IgG1
    VS7-0425-WR115 Mouse Anti-IDH2 Recombinant Antibody (clone 3E8E9) IHC, FC Mouse IgG1

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