Mouse Anti-IGF2BP3 Monoclonal Antibody (VS7-0425-WR119)
CAT#: VS7-0425-WR119
This product is a mouse IgG antibody that binds to human EPAS1. The antibody 1H3E62 can be used for WB, IHC-P, IF, and ELISA assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2037/if_selected.jpg
Normal Tissue
Figure 2 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_7_5.jpg
Normal Tissue
Figure 3 Placenta
Cytotrophoblasts Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Hofbauer cells Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_1_7.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HUVEC TERT2)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136231-IGF2BP3
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Specifications
- Immunogen
- Recombinant human IGF2BP3 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IGF2BP3
- Species Reactivity
- Human
- Molecule Class
- Rna-Binding Protein
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Hepatocellular carcinoma; Colorectal cancer; Lung cancer; Pancreatic cancer; Glioma; Acute myeloid leukemia (AML)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- 1 mg/mL
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000
Immunohistochemistry: 1:200 - 1:1000
Target
- Alternative Names
- KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
- Gene ID
- 10643
- UniProt ID
- O00425
- Long Name
- Insulin Like Growth Factor 2 Mrna Binding Protein 3
- Cellular Localization
- Cytoplasm; Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_006538.2
- Function
- RNA-binding
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "IGF2BP3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1758 | Rabbit Anti-IGF2BP3 Recombinant Antibody (clone DS1758AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0839-CN | Mouse Anti-IGF2BP3 Recombinant Antibody (clone C2-E4) | WB, IHC, IF, FC | Mouse IgG1 |
| MRO-1975-CN | Rabbit Anti-IGF2BP3 Polyclonal Antibody (MRO-1975-CN) | WB, IHC, FC | Rabbit IgG |
| VS3-QX583 | Mouse Anti-IGF2BP3 Recombinant Antibody (clone 1F1-E10-D11) | WB | Mouse IgG1 |
| VS3-FY737 | Recombinant Mouse Anti-IGF2BP3 Antibody (clone 1B4D5) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-FY738 | Recombinant Mouse Anti-IGF2BP3 Antibody (clone 2A1B9) | ELISA, WB, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1104 | Anti-IGF2BP3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3438 | Anti-Human IGF2BP3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC572 | CytoStream™ Rabbit Anti-IGF2BP3 Polyclonal Antibody (VS13-YC572) | WB, IF, IP, FC | Rabbit IgG |
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