Mouse Anti-IGF2BP3 Monoclonal Antibody (VS7-0425-WR119) (CAT#: VS7-0425-WR119)
This product is a mouse IgG antibody that binds to human EPAS1. The antibody 1H3E62 can be used for WB, IHC-P, IF, and ELISA assays.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2037/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2037/if_selected.jpg
Figure 2 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_7_5.jpg
Figure 3 Placenta
(Cytotrophoblasts Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Hofbauer cells Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_1_7.jpg
(Cytotrophoblasts Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Hofbauer cells Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_1_7.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76951/168373_A_8_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HUVEC TERT2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136231-IGF2BP3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136231-IGF2BP3
Specifications
- Immunogen
- Recombinant human IGF2BP3 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IGF2BP3
- Species Reactivity
- Human
- Molecule Class
- Rna-Binding Protein
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Hepatocellular carcinoma; Colorectal cancer; Lung cancer; Pancreatic cancer; Glioma; Acute myeloid leukemia (AML)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- 1 mg/mL
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000
Immunohistochemistry: 1:200 - 1:1000
Target
- Alternative Names
- KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
- Gene ID
- 10643
- UniProt ID
- O00425
- Long Name
- Insulin Like Growth Factor 2 Mrna Binding Protein 3
- Cellular Localization
- Cytoplasm; Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_006538.2
- Function
- RNA-binding
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0312MZ | Recombinant Mouse Anti-Human IGF2BP3 Antibody (clone A70.2) | IHC | Mouse antibody |
| MRO-0839-CN | Mouse Anti-IGF2BP3 Recombinant Antibody (clone C2-E4) | WB, IHC, IF, FC | Mouse IgG1 |
| VS3-QX583 | Mouse Anti-IGF2BP3 Recombinant Antibody (clone 1F1-E10-D11) | WB | Mouse IgG1 |
| VS3-FY737 | Recombinant Mouse Anti-IGF2BP3 Antibody (clone 1B4D5) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-FY738 | Recombinant Mouse Anti-IGF2BP3 Antibody (clone 2A1B9) | ELISA, WB, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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