Rabbit Anti-IL1RN Recombinant Antibody (clone R01-6J5) (CAT#: VS3-FY1749)

• Immunogen
• Synthetic peptide of human IL1RA

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human and Mouse IL1RN

• Species Reactivity
• Human, Mouse

• Clone
• R01-6J5

• Applications
• Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 20 kDa, while the observed molecular weight stands at 20 kDa.

• Related Disease
• Cancer

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunohistochemistry: 1/50-1/100
  Immunofluorescence: 1/50-1/200
  Immunoprecipitation: 1/20

• Alternative Names
• Interleukin 1 Receptor Antagonist

• Gene ID
• 3557

• UniProt ID
• P18510

• Sequence Similarities
• Belongs to the IL-1 family.

• Cellular Localization
• Cytoplasm, Secreted

• Post Translation Modifications
• Disulfide bond
  Glycoprotein

• Protein Refseq
• XP_011509423.1; XP_047300140.1; XP_047300141.1; XP_047300142.1; NP_000568.1

• Function
• Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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