Recombinant Rabbit Anti-IL1RN Detection Antibody (clone R05-7M2) (CAT#: VS3-WK1727)
This antibody is a rabbit recombinant antibody against human IL1RN. It was developed by immunization of rabbit with recombinant human IL1RN protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R02-6W5 and R05-7M2 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R05-7M2 can be used in ELISA analysis to identify human IL1RN.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm, cytosol & centrosome.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/1422_G7_6_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm, cytosol & centrosome.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/1422_G7_6_selected.jpg
Figure 2 High expression in esophagus
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4971_B_5_1.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4971_B_5_1.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4626_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4626_A_9_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (A-431, HaCaT, RT4, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136689-IL1RN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136689-IL1RN
Specifications
- Immunogen
- Recombinant human IL1RN protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL1RN
- Species Reactivity
- Human
- Clone
- R05-7M2
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 1 Receptor Antagonist
- Gene ID
- 3557
- UniProt ID
- P18510
- Long Name
- Interleukin 1 Receptor Antagonist
- Sequence Similarities
- Belongs to the IL-1 family.
- Cellular Localization
- Cytoplasm, Secreted
- Protein Refseq
- NP_000568.1
- Function
- Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Recommended Products
Capture antibody
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL1RN"
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Please select product type
IgG Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1402z | Mouse Anti-IL1RN Recombinant Antibody (clone 8C2) | WB, IHC | Mouse IgG2b |
| MOB-0238CT | Recombinant Mouse anti-Human IL1RN Monoclonal antibody (B82C7E22) | ELISA | |
| VS3-FY1749 | Rabbit Anti-IL1RN Recombinant Antibody (clone R01-6J5) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| VS3-WK1726 | Recombinant Rabbit Anti-IL1RN Capture Antibody (clone R02-6W5) | ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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