Rabbit Anti-KDM4B Recombinant Antibody (clone R08-9G9) (CAT#: VS3-FY1756)
This marvelous recombinant antibody is crucial for validating in immunohistochemistry (IHC) studies. As a rabbit recombinant monoclonal antibody that is designed to target human KDM4B. It is suitable for use in a variety of assays, including WB, IHC-F, IHC-P, ICC/IF. This R08-9G9 antibody is validated for western blot analysis of KDM4B in 293, COS7 lysates.
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WB
Figure 1 Anti-KDM4B Antibody (VS3-FY1756) in WB.
The KDM4B expression in 293, COS7 lysates were detected using the anti-KDM4B by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human KDM4B/JMJD2B
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human KDM4B
- Species Reactivity
- Human
- Clone
- R08-9G9
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
- MW
- The calculated weight of the target protein is approximately 122 kDa, while the observed molecular weight stands at 150 kDa.
- Related Disease
- Intellectual Developmental Disorder, Autosomal Dominant 65 and Non-Specific Syndromic Intellectual Disability
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- Lysine Demethylase 4B; JmjC Domain-Containing Histone Demethylation Protein 3B; Jumonji Domain-Containing Protein 2B; Lysine (K)-Specific Demethylase 4B; Jumonji Domain Containing 2B; Tudor Domain Containing 14B; JMJD2B
- Gene ID
- 23030
- UniProt ID
- O94953
- Sequence Similarities
- Belongs to the JHDM3 histone demethylase family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Acetylation
Phosphoprotein
- Protein Refseq
- XP_005259578.2; XP_011526116.1; XP_011526119.1; XP_011526121.1; XP_011526122.1
- Function
- Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-376 | Recombinant Human Anti-Human KDM4B Antibody, clone D437 | ELISA, IP-MS | IgG |
| VS7-0425-WR202 | Mouse Anti-KDM4B Recombinant Antibody (clone 3A6H6) | FC | Mouse IgG1 |
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