Mouse Anti-KLK3 Recombinant Antibody (clone 1L123H-f) (CAT#: FAMAB-0159JF)

Recombinant monoclonal antibody specifically binds to prostate-specific antigen (PSA). This mouse anti-PSA antibody (1L123H-f) can detect the fraction of PSA in human sera.


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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 VEGF-C activation by KLK3 is enhanced by CCBE1.

Figure 1 VEGF-C activation by KLK3 is enhanced by CCBE1.

Activation of VEGF-C by KLK3 is enhanced by CCBE1.

Jha, S. K., Rauniyar, K., Chronowska, E., Mattonet, K., Maina, E. W., Koistinen, H., ... & Jeltsch, M. (2019). KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. Elife, 8, e44478.

ELISA

Figure 2 The receptor-activating properties of VEGF-C are differentially affected by cathepsin D cleavage.

Figure 2 The receptor-activating properties of VEGF-C are differentially affected by cathepsin D cleavage.

Shown are the results of Ba/F3-VEGFR/EpoR assays used to evaluate the receptor-activating properties of cathepsin D- and KLK3- cleaved proteins.

Jha, S. K., Rauniyar, K., Chronowska, E., Mattonet, K., Maina, E. W., Koistinen, H., ... & Jeltsch, M. (2019). KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. Elife, 8, e44478.

IF

Figure 3 The KLK3- and cathepsin D-forms of VEGF-C induce lymphangiogenesis and angiogenesis in vivo.

Figure 3 The KLK3- and cathepsin D-forms of VEGF-C induce lymphangiogenesis and angiogenesis in vivo.

Shown are the immunofluorescent stainings of the blood and lymphatic vessels in skeletal muscle.

Jha, S. K., Rauniyar, K., Chronowska, E., Mattonet, K., Maina, E. W., Koistinen, H., ... & Jeltsch, M. (2019). KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. Elife, 8, e44478.


Specifications

  • Immunogen
  • Human kallikrein related peptidase 3
  • Host Species
  • Mouse
  • Derivation
  • Mouse phage display scFv library
  • Type
  • Mouse IgG
  • Specificity
  • Human PSA
  • Species Reactivity
  • Human
  • Clone
  • 1L123H-f
  • Applications
  • WB, ELISA, IF
  • Related Disease
  • Prostatic diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The KLK3 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunofluorescence.

Target

  • Alternative Names
  • APS; PSA; hK3; KLK2A1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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