Mouse Anti-KRT20 Recombinant Antibody (VS3-FY2758) (CAT#: VS3-FY2758)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Keratin 20 of human

• Species Reactivity
• Human

• Applications
• IHC, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 48.5 kDa.

• Related Disease
• Cancer

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Immunohistochemistry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• Keratin 20; Keratin 20, Type I; Protein IT; CK-20; K20; Keratin, Type I Cytoskeletal 20; Cytokeratin 20

• Gene ID
• 54474

• Sequence Similarities
• Belongs to the intermediate filament family.

• Cellular Localization
• Cytoplasm, Intermediate filament, Keratin

• Post Translation Modifications
• Hyperphosphorylation at Ser-13 ^oCcurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury (By similarity).
  Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.

• Protein Refseq
• NP_061883.1

• Function
• Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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