Human Anti-LILRB4 Recombinant Antibody scFv Fragment (PABJ-0128-S(P)) (CAT#: PABJ-0128-S(P))
This product is a Human antibody scFv fragment that recognizes Human LILRB4. This antibody showed potent activity in blocking development of monocytic AML in various models including patient-derived xenograft (PDX) mice and syngeneic immunocompetent AML mice. It enhanced the anti-AML efficacy of chemotherapy treatment by stimulating mobilization of leukemia cells.
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RNA Expression
Figure 1 RNA cell line category: Cell line enriched (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186818-LILRB4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186818-LILRB4
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human LILRB4
- Species Reactivity
- Human
- Applications
- ELISA, Block, ADCC
- Related Disease
- Acute myeloid leukemia
Product Property
- Purification
- Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Blocking, Antibody-dependent cellular cytotoxicity.
Target
- Alternative Names
- ILT3; LIR5; CD85K; ILT-3; LIR-5; leukocyte immunoglobulin-like receptor subfamily B member 4; CD85 antigen-like family member K; immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin-like receptor 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; monocyte inhibitory receptor HM18
- Gene ID
- 11006
- UniProt ID
- Q8NHJ6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1298-VHH | Recombinant Anti-Human LILRB4 VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
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For Research Use Only. Not For Clinical Use.
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