Mouse Anti-MAP3K7 Recombinant Antibody (clone 3E8H4)
CAT#: VS7-0425-WR345
This product is a mouse IgG2a antibody that binds to human MAP3K7. The antibody 3E8H4 recognizes specific amino acid domain of human MAP3K7 (AA: 471-579). It can be used for WB and ELISA assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7633/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75335/1835_D4_7_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7633/21509_A_4_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7633/21509_B_9_5.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135341-MAP3K7
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Specifications
- Immunogen
- Recombinant human MAP3K7 (AA: 471-579) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human MAP3K7
- Species Reactivity
- Human
- Clone
- 3E8H4
- Molecule Class
- Serine/Threonine Protein Kinase
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Frontometaphyseal dysplasia 2 (FMD2); Cardiospondylocarpofacial syndrome (CSCF)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- CSCF; FMD2; TAK1; MEKK7; TGF1a
- Gene ID
- 6885
- UniProt ID
- O43318
- Long Name
- Mitogen-Activated Protein Kinase Kinase Kinase 7
- Cellular Localization
- Cell membrane; Cytoplasm; Membrane
- Post Translation Modifications
- Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_003179.1
- Function
- Kinase; Serine/threonine-protein kinase; Transferase
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Related Diseases
Endometrial Cancer
Throid Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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Secondary Antibody
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Reconstitution Buffer
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See other products for "MAP3K7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2143 | Hi-Affi™ Recombinant Rabbit Anti-MAP3K7 Monoclonal Antibody (DS2143AB) | WB, IHC-P, ICC | IgG |
| MOR-4749 | Hi-Affi™ Recombinant Rabbit Anti-MAP3K7 Monoclonal Antibody (TH263DS) | WB, IF, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1033 | Mouse Anti-MAP3K7 Recombinant Antibody (clone 1G5) | WB, IP, IF | Mouse IgG1 |
| VS3-XY1034 | Mouse Anti-MAP3K7 Recombinant Antibody (clone 1H6H6) | ELISA, WB | Mouse IgG2a |
| VS3-XY1035 | Mouse Anti-MAP3K7 Recombinant Antibody (clone 4E7E10) | ELISA, WB | Mouse IgG2a |
| VS3-XY3426 | Rabbit Anti-MAP3K7 Recombinant Antibody (clone R09-4G4) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
| VS3-WK2277 | Rabbit Anti-MAP3K7 (pS439) Recombinant Antibody (VS3-WK2277) | WB, ICC, IP | Rabbit IgG |
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