Mouse Anti-MAP3K8 Recombinant Antibody (clone CBM991)
CAT#: MOB-204YJL
This product is a Mouse antibody that recognizes Human MAP3K8.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows cytoplasmic positivity in germinal center cells and non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_5_8_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17962/40494_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HMC-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107968-MAP3K8
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Specifications
- Immunogen
- E. coli-derived recombinant human MAP3K8/Tpl2/COT, AA Gln173-Gln395.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human MAP3K8
- Species Reactivity
- Human
- Clone
- CBM991
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A/G purified
- Format
- Lyophilized
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Mitogen-Activated Protein Kinase Kinase Kinase 8; Tumor Progression Locus; Proto-Oncogene C-Cot; Tpl-2; ESTF; COT; Proto-Oncogene Serine/Threoine Protein Kinase; Augmented In Rheumatoid Arthritis 2; Cot (Cancer Osaka Thyroid) Oncogene; Serine/Threonine-Protein Kinase Cot; Cancer Osaka Thyroid Oncogene; Ewing Sarcoma Transformant; EC 2.7.11.25; AURA2; MEKK8; C-COT; TPL2; EST
- Gene ID
- 1326
- UniProt ID
- P41279
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Related Diseases
Endometrial Cancer
Throid Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MAP3K8"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2144 | Hi-Affi™ Recombinant Rabbit Anti-MAP3K8 Monoclonal Antibody (DS2144AB) | WB | IgG |
| MOR-4558 | Hi-Affi™ Recombinant Rabbit Anti-MAP3K8 Monoclonal Antibody (TH68DS) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4222 | Anti-MAP3K8 Immunohistochemistry Kit | IHC |
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