Mouse Anti-MAP4K5 Recombinant Antibody (MA1082)
CAT#: VS-0326-YC1082
The anti-MAP4K5 recombinant antibody (MA1082) reacts with human MAP4K5. MAP4K5 (KHS1) is a member of the GCK family of kinases that activates the JNK stress-response pathway. It is involved in environmental stress sensing and the regulation of immune cell activation. MAP4K5 signaling has been implicated in the inflammatory response and the modulation of cell survival under oxidative stress. The anti-MAP4K5 antibody (MA1082) has been tested in Immunohistochemistry (IHC).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36696/410_E6_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78030/1893_C16_1_cr5bc06be7749a5_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36696/75226_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36696/75226_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36696/75226_A_5_6.jpg
Normal Tissue
Figure 6 Ovary
Follicle cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36696/75226_A_4_7.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000012983-MAP4K5
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MAP4K5
- Species Reactivity
- Human
- Clone
- MA1082
- Applications
- IHC
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- IHC (1/100-1/200)
Target
- Alternative Names
- Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5; Kinase Homologous To SPS1/STE20; MAPK/ERK Kinase Kinase Kinase 5; Germinal Center Kinase-Related; MEK Kinase Kinase 5; EC 2.7.11.1; MEKKK 5;
- Gene ID
- 11183
- UniProt ID
- Q9Y4K4
- Long Name
- Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "MAP4K5"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1178CT | Recombinant Mouse anti-Human MAP4K5 Monoclonal antibody (EML1194) | WB |
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