AbPlus™ Anti-MAPK14 Magnetic Beads (VS-0724-YC1292) (CAT#: VS-0724-YC1292)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-MAPK14 specific antibody

• Target
• MAPK14

• Immunogen
• Recombinant human p38 alpha/MAPK14, aa 1-360.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Alternative Names
• Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase P38 Alpha; MAX-Interacting Protein 2; CSAID-Binding Protein; MAP Kinase P38 Alpha; P38 MAP Kinase; MAP Kinase 14; EC 2.7.11.24; SAPK2A; CSBP1; CSBP2; CSPB1; CSBP; Mxi2; Cytokine Suppressive Anti-Inflammatory Drug Binding Protein; Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein;

• Gene ID
• 1432

• UniProt ID
• Q16539

Select a product category from the dropdown menu below to view related products.