Anti-MITF (clone W24V191) Recombinant Antibody Coupled Liposome (VS-1024-FY192)
CAT#: VS-1024-FY192
Anti-MITF antibody conjugated liposomes serve as a targeted delivery system for therapies aimed at melanoma, focusing on the microphthalmia-associated transcription factor (MITF). By directing the liposomes to MITF-expressing melanoma cells, they improve drug concentration at the site of action. This strategy enhances efficacy while reducing toxicities associated with systemic treatment. Ultimately, it holds potential for improving patient outcomes in melanoma therapy.
Gene Expression
Normal Tissue
Figure 1 Cervix
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3259/10295_B_7_3_val_selected.jpg
Normal Tissue
Figure 2 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2578/6353_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3259/10268_A_8_5.jpg
Normal Tissue
Figure 4 Skin
Fibrohistiocytic cells Staining: Low Intensity: Weak Melanocytes Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2578/6353_B_8_1.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2578/6353_A_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000187098-MITF
❮
❯
More Infomation
Specifications
- Potential Clinical Applications
- Melanoma
Product Composition
- Clone
- W24V191
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was specifically engineered to target the Melanocyte Inducing Transcription Factor (MITF). MITF plays a crucial role in the regulation of melanocyte development, function, and survival, making it a significant marker in studies related to pigmentation, melanoma, and other skin-related conditions.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- MITF
- Introduction
- The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
- Alternative Names
- Melanogenesis Associated Transcription Factor; Microphthalmia-Associated Transcription Factor; Class E Basic Helix-Loop-Helix Protein 32; BHLHe32; Microphtalmia-Associated Transcription Factor; Homolog Of Mouse Microphthalmia; Waardenburg Syndrome, Type 2A
- Full Name
- Melanogenesis Associated Transcription Factor
- Gene ID
- 4286
- UniProt ID
- O75030
- Cellular Localization
- Cytoplasm, Nucleus
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-1024-FY192. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MITF"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0327MZ | Recombinant Mouse Anti-Human MITF Antibody (clone E6) | IHC | Mouse antibody |
| ZG-0774F | Mouse Anti-MITF Recombinant Antibody (clone C5) | WB, IP, IHC, GS | Mouse IgG1 |
| ZG-0782F | Mouse Anti-MITF Antibody (clone C5/D5 Cocktail) | IHC, IP, WB, GS | Mouse IgG1 |
| ZG-0788F | Mouse Anti-MITF Recombinant Antibody (clone D5) | IHC, GS, WB, IP | Mouse IgG1 |
| VS3-WK417 | Rabbit Anti-MITF Recombinant Antibody (clone JF100-01) | WB, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0362MZ | Chicken Anti-MITF Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2236 | Hi-Affi™ Recombinant Rabbit Anti-MITF Monoclonal Antibody (DS2236AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY187 | AbPlus™ Anti-MITF Magnetic Beads (C5) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC729 | CytoStream™ Rabbit Anti-MITF Recombinant Antibody (VS13-YC729) | WB, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4402 | Anti-MITF Immunohistochemistry Kit | IHC |
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
