Mouse Anti-MMACHC Recombinant Antibody (clone mN230/21) (CAT#: VS-0422-LC148)
The purified mouse Anti-MMACHC recombinant antibody (clone mN230/21) product displayed high specificity against the MMACHC protein of human, mouse.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27394/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27394/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/if_selected.jpg
Figure 3 IHC staining of human stomach, lower
(Immunohistochemical staining of human stomach, lower shows moderate cytoplasmic and nucleolar positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27394/ihc_selected.jpg
(Immunohistochemical staining of human stomach, lower shows moderate cytoplasmic and nucleolar positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27394/ihc_selected.jpg
Figure 4 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27402/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27402/ihc_selected.jpg
Figure 5 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_9_8.jpg
Figure 6 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_8_3.jpg
Figure 7 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27399/61028_A_6_6.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000132763-MMACHC
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000132763-MMACHC
Specifications
- Immunogen
- A fusion protein amino acids 1-282 (full-length) of human MMACHC.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MMACHC
- Species Reactivity
- Human, Mouse
- Clone
- mN230/21
- Applications
- WB
- Conjugate
- Unconjugated
- Related Disease
- Methylmalonic Aciduria And Homocystinuria, Cblc Type and Disorders Of Intracellular Cobalamin Metabolism
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Concentration
- 1 mg/mL
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot.
Target
- Alternative Names
- CblC; cyanocobalamin reductase; alkylcobalamin dealkylase; alkylcobalamin:glutathione S-alkyltransferase; cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; EC 1.16.1.6; EC 2.5.1.151
- Gene ID
- 25974
- UniProt ID
- Q9Y4U1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2245 | Hi-Affi™ Recombinant Rabbit Anti-MMACHC Monoclonal Antibody (DS2245AB) | WB, IP | IgG |
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