Mouse Anti-MMP1 Recombinant Antibody (VS3-CJ320) (CAT#: VS3-CJ320)

• Immunogen
• Recombinant protein from human

• Host Species
• Mouse

• Type
• Mouse IgG2a

• Specificity
• Human MMP1

• Species Reactivity
• Human

• Applications
• WB

• Conjugate
• Unconjugated

• Purification
• Affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Buffer
• PBS

• Preservative
• 0.09% sodium azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• This antibody has been tested for use in Western Blot (1:2000).

• Alternative Names
• CLG; CLGN

• Gene ID
• 4312

• UniProt ID
• P03956

• Sequence Similarities
• Belongs to the peptidase M10A family.

• Cellular Localization
• Extracellular matrix, Secreted

• Post Translation Modifications
• Undergoes autolytic cleavage to two major forms (22 kDa and 27 kDa). A minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.
  Tyrosine phosphorylated in platelets by PKDCC/VLK.

• Protein Refseq
• NP_002412.1

• Function
• Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757).
  In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369).

Secondary Antibody

• 2RD-A1464-YJ
• Goat Anti-Mouse IgG2a Secondary antibody

• 2RD-A1564-YJ
• Rabbit Anti-Mouse IgG2a Secondary antibody (Clone RM219)

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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