Mouse Anti-MMP1 Recombinant Antibody (VS3-CJ320) (CAT#: VS3-CJ320)
This product is a mouse antibody that recognizes MMP1.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4920/1_B2_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4920/1_B2_2_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (BJ hTERT+, HBF TERT88, HUVEC TERT2, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196611-MMP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196611-MMP1
Specifications
- Immunogen
- Recombinant protein from human
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human MMP1
- Species Reactivity
- Human
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:2000).
Target
- Alternative Names
- CLG; CLGN
- Gene ID
- 4312
- UniProt ID
- P03956
- Sequence Similarities
- Belongs to the peptidase M10A family.
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- Undergoes autolytic cleavage to two major forms (22 kDa and 27 kDa). A minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.
Tyrosine phosphorylated in platelets by PKDCC/VLK.
- Protein Refseq
- NP_002412.1
- Function
- Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757).
In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369).
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MMP1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1937MZ | Recombinant Mouse Anti-Human MMP1 Antibody (clone 4B0.4) | WB | Mouse antibody |
| MRO-2036-CN | Rabbit Anti-MMP1 Polyclonal Antibody (MRO-2036-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0716F | Mouse Anti-MMP1 Recombinant Antibody (clone 3B6) | WB, IHC | Mouse IgG1 |
| VS3-QX777 | Mouse Anti-MMP1 Recombinant Antibody (clone 6A5) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1742CQ | Recombinant Mouse Anti-MMP1 Antibody (CBL461) | WB, IHC, IP, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2247 | Hi-Affi™ Recombinant Rabbit Anti-MMP1 Monoclonal Antibody (DS2247AB) | FC, ICC, IHC-Fr, IHC-P, IP, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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