Mouse Anti-MPO Recombinant Antibody (clone PT2243)
CAT#: VS3-CJ402
This product is a mouse antibody that recognizes MPO.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61464/1487_B11_3_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61464/1403_F7_1_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61464/1398_F7_1_red_green.jpg
Normal Tissue
Figure 4 Bone marrow
Hematopoietic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61464/145726_B_6_4.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21147/146573_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HL-60, NB-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005381-MPO
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Specifications
- Immunogen
- Synthesized peptide derived from human Myeloperoxidase (MPO)
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human MPO
- Species Reactivity
- Human
- Clone
- PT2243
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- Myeloperoxidase
- Gene ID
- 4353
- UniProt ID
- P05164
- Sequence Similarities
- Belongs to the peroxidase family. XPO subfamily.
- Cellular Localization
- Lysosome
- Protein Refseq
- NP_000241.1
- Function
- Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160).
Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "MPO"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1015 | Recombinant Mouse Anti-Human MPO Antibody Fab Fragment | LMNX, ELISA | Fab |
| FAMAB-0256WJ-F(E) | Human Anti-MPO Recombinant Antibody (clone E3-MPO); Fab Fragment | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2273 | Hi-Affi™ Recombinant Rabbit Anti-MPO Monoclonal Antibody (DS2273AB) | ICC, IHC-P, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1223CQ | Human Anti-MPO Recombinant Antibody (clone 1E8) | ELISA | Human IgG1 |
| MOB-0129F | Mouse Anti-MPO Recombinant Antibody (MOB-0129F) | IHC-P, IF | Mouse IgG |
| MOB-0130F | Mouse Anti-MPO Recombinant Antibody (MOB-0130F) | IHC-P, IF | Mouse IgG |
| VS3-FY942 | Recombinant Mouse Anti-MPO Antibody (clone 9D10-2F3-3E7) | IHC-P | Mouse IgG1 |
| VS3-FY943 | Recombinant Rabbit Anti-MPO Antibody (clone R03-6F2) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0256WJ-S(P) | Human Anti-MPO Recombinant Antibody (clone E3-MPO); scFv Fragment | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0622WJ | Mouse Anti-MPO Recombinant Antibody (clone 6D6) | ELISA, WB, IF | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY164 | CytoStream™ Mouse Anti-MPO Recombinant Antibody (clone 8F4/MPO) | FC | Mouse IgG1, kappa |
| VS13-YC738 | CytoStream™ Mouse Anti-MPO Recombinant Antibody (VS13-YC738) | WB, IHC-P, ICC, IF, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1365 | Anti-MPO Immunohistochemistry Kit | IHC | |
| VS-0525-XY4482 | Anti-Mouse MPO Immunohistochemistry Kit | IHC | |
| VS-0525-XY4481 | Anti-Human MPO Immunohistochemistry Kit | IHC | |
| VS-0525-XY4483 | Anti-Rat MPO Immunohistochemistry Kit | IHC |
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