Human Anti-MRC1 Antibody (B11), CHO Stable Cell Pool

Name: Human Anti-MRC1 Antibody (B11), CHO Stable Cell Pool
SKU: VS-1025-QX247
Rating: 5 (1 reviews)

CAT#: VS-1025-QX247

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant B11. B11 is a Human monoclonal antibody that targets MRC1. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of B11 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Normal Tissue Figure 1 IHC staining of human lung

High expression. RNA expression: 122.3 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_A_1_4_selected.jpg

Normal Tissue Figure 2 IHC staining of human skin

Low expression. RNA expression: 2.8 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_B_8_1_val_selected.jpg

Normal Tissue Figure 3 Colon

Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45134/155703_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45134/155703_A_8_5.jpg

Normal Tissue Figure 5 Testis

Elongated or late spermatids
Staining: Low
Intensity: Moderate
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Group enriched (MOLT-4, TIME)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000260314-MRC1

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG1, κ

Clone
B11

Target
MRC1

Species Reactivity
Human

Target

Alternative Names
MRC1; mannose receptor, C type 1; MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; macrophage mannose receptor 1; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1

Gene ID
4360

UniProt ID
P22897

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Datasheet

Datasheet - VS-1025-QX247.pdf

MSDS

MSDS - VS-1025-QX247.pdf

COA

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