This product is a mouse monoclonal antibody targeting human MSMP. This antibody can be used for treating various MSMP-related diseases and can be further used for detecting the content of MSMP protein in samples.
Figure 1 Mouse mAbs targeting PSMP (3D5, 4E7, and 2G11) were applied in the chemotaxis assay.
PSMP (7, 70, or 700 ng/ml) was pretreated with 3D5, 4E7, or 2G11 (10 or 50 µg/ml) for 30 min, and the chemotaxis index and the significant difference were calculated.
Pei, X., Sun, Q., Zhang, Y., Wang, P., Peng, X., Guo, C., ... & Chen, D. (2014). PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2. The Journal of Immunology, 192(4), 1878-1886.
Figure 2 PSMP upregulates p-ERK in the PC3 cell line.
Before stimulating PC3 cells with PSMP, the PSMP protein was treated with mouse mAbs against PSMP (3D5 or 4E7), or PC3 cells were treated with the CCR2B inhibitor RS102895. The p-ERK and ERK1/2 levels were detected by Western blot after stimulation.
Pei, X., Sun, Q., Zhang, Y., Wang, P., Peng, X., Guo, C., ... & Chen, D. (2014). PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2. The Journal of Immunology, 192(4), 1878-1886.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0286-WJ | Mouse Anti-MSMP Recombinant Antibody (clone 4E7) | FuncS, WB | Human IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0285-WJ-S(P) | Mouse Anti-MSMP Recombinant Antibody (clone 3D5); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-0286-WJ-S(P) | Mouse Anti-MSMP Recombinant Antibody (clone 4E7); scFv Fragment | ELISA, Neut | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0285-WJ-F(E) | Mouse Anti-MSMP Recombinant Antibody (clone 3D5); Fab Fragment | ELISA, Neut | Mouse Fab |
HPAB-0286-WJ-F(E) | Mouse Anti-MSMP Recombinant Antibody (clone 4E7); Fab Fragment | ELISA, Neut | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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