Rabbit Anti-MXD3 Recombinant Antibody (clone R07-6H7) (CAT#: VS3-FY2026)
The anti-MXD3 recombinant rabbit recombinant monoclonal antibody is purified by affinity chromatography. It binds strongly to human MXD3. The calculated molecular weight of the antigen is 23 kDa; the observed molecular weight of the protein is 23 kDa.
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WB
Figure 1 Anti-MXD3 Antibody (VS3-FY2026) in WB.
The MAD3 expression in Hela, A549, HL-60 lysates were detected using the anti-Max Dimerization Protein 3 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human MAD3
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MXD3
- Species Reactivity
- Human
- Clone
- R07-6H7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 23 kDa, while the observed molecular weight stands at 23 kDa.
- Related Disease
- Atrichia With Papular Lesions and Medulloblastoma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- MAX Dimerization Protein 3; Max-Interacting Transcriptional Repressor MAD3; Class C Basic Helix-Loop-Helix Protein 13; Max-Associated Protein 3; Max Dimerizer 3; BHLHC13; MAD3; MYX
- Gene ID
- 83463
- UniProt ID
- Q9BW11
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Ubiquitination at Lys81 and Lys108 (NX_Q9BW11 [NX_Q9BW11-1])
Modification sites at PhosphoSitePlus (Q9BW11)
- Protein Refseq
- NP_001136407.1; NP_001381915.1; NP_001381916.1; NP_112590.1
- Function
- Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4020z | Mouse Anti-MXD3 Recombinant Antibody (MOB-4020z) | WB, ICC | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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