Rabbit Anti-MXD3 Recombinant Antibody (clone R07-6H7) (CAT#: VS3-FY2026)
The anti-MXD3 recombinant rabbit recombinant monoclonal antibody is purified by affinity chromatography. It binds strongly to human MXD3. The calculated molecular weight of the antigen is 23 kDa; the observed molecular weight of the protein is 23 kDa.
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WB
Figure 1 Anti-MXD3 Antibody (VS3-FY2026) in WB.
The MAD3 expression in Hela, A549, HL-60 lysates were detected using the anti-Max Dimerization Protein 3 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human MAD3
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MXD3
- Species Reactivity
- Human
- Clone
- R07-6H7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 23 kDa, while the observed molecular weight stands at 23 kDa.
- Related Disease
- Atrichia With Papular Lesions and Medulloblastoma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- MAX Dimerization Protein 3; Max-Interacting Transcriptional Repressor MAD3; Class C Basic Helix-Loop-Helix Protein 13; Max-Associated Protein 3; Max Dimerizer 3; BHLHC13; MAD3; MYX
- Gene ID
- 83463
- UniProt ID
- Q9BW11
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Ubiquitination at Lys81 and Lys108 (NX_Q9BW11 [NX_Q9BW11-1])
Modification sites at PhosphoSitePlus (Q9BW11)
- Protein Refseq
- NP_001136407.1; NP_001381915.1; NP_001381916.1; NP_112590.1
- Function
- Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
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FC Reagents & Kits
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4020z | Mouse Anti-MXD3 Recombinant Antibody (MOB-4020z) | WB, ICC | Mouse IgG2b |
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