CytoStream™ Rabbit Anti-MXD3 Recombinant Antibody (VS13-YC752) (CAT#: VS13-YC752)
The CytoStream™ Rabbit Anti-MXD3 Recombinant Antibody is specific for human, mouse and rat MXD3. MXD3 encodes a Myc family transcriptional regulator, functioning with MAX to bind DNA motifs, linked to cell proliferation control. The anti-MXD3 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70111/1443_B7_1_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70111/1443_B7_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213347-MXD3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213347-MXD3
Specifications
- Immunogen
- Recombinant human MAD3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MXD3
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
- Related Disease
- Atrichia With Papular Lesions and Medulloblastoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- MAX Dimerization Protein 3; Max-Interacting Transcriptional Repressor MAD3; Class C Basic Helix-Loop-Helix Protein 13; Max-Associated Protein 3; Max Dimerizer 3; BHLHC13; MAD3; MYX;
- Gene ID
- 83463
- UniProt ID
- Q9BW11
- Long Name
- MAX Dimerization Protein 3
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_001136407.1; NP_001381915.1; NP_001381916.1; NP_112590.1
- Function
- Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4020z | Mouse Anti-MXD3 Recombinant Antibody (MOB-4020z) | WB, ICC | Mouse IgG2b |
| VS3-FY2026 | Rabbit Anti-MXD3 Recombinant Antibody (clone R07-6H7) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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