CytoStream™ Rabbit Anti-MXD3 Recombinant Antibody (VS13-YC752) (CAT#: VS13-YC752)
The CytoStream™ Rabbit Anti-MXD3 Recombinant Antibody is specific for human, mouse and rat MXD3. MXD3 encodes a Myc family transcriptional regulator, functioning with MAX to bind DNA motifs, linked to cell proliferation control. The anti-MXD3 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70111/1443_B7_1_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70111/1443_B7_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213347-MXD3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213347-MXD3
Specifications
- Immunogen
- Recombinant human MAD3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MXD3
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
- Related Disease
- Atrichia With Papular Lesions and Medulloblastoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- MAX Dimerization Protein 3; Max-Interacting Transcriptional Repressor MAD3; Class C Basic Helix-Loop-Helix Protein 13; Max-Associated Protein 3; Max Dimerizer 3; BHLHC13; MAD3; MYX;
- Gene ID
- 83463
- UniProt ID
- Q9BW11
- Long Name
- MAX Dimerization Protein 3
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_001136407.1; NP_001381915.1; NP_001381916.1; NP_112590.1
- Function
- Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Fab Antibodies
ScFv Antibodies
Rabbit Monoclonal Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4020z | Mouse Anti-MXD3 Recombinant Antibody (MOB-4020z) | WB, ICC | Mouse IgG2b |
| VS3-FY2026 | Rabbit Anti-MXD3 Recombinant Antibody (clone R07-6H7) | WB | Rabbit IgG |
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