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    Mouse Anti-MYB Recombinant Antibody (VS3-CJ555) (CAT#: VS3-CJ555)

    This product is a mouse antibody that recognizes human MYB (Center).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line REH
    Figure 1 IF staining of human cell line REH
    (Immunofluorescent staining of human cell line REH shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71605/1817_A4_6_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human rectum
    Figure 2 IHC staining of human rectum
    (Immunohistochemical staining of human rectum shows nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_5_3_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_9_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_6_6.jpg
    Figure 8 Bone marrow
    Figure 8 Bone marrow
    (Hematopoietic cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_B_6_4.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17704/41000_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (HL-60, MOLT-4, NB-4, REH, THP-1, U-937)
    Figure 10 RNA cell line category: Cell line enhanced (HL-60, MOLT-4, NB-4, REH, THP-1, U-937)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118513-MYB

    Specifications

    • Immunogen
    • KLH-conjugated synthetic peptide between 1-185 amino acids from the Central region of human MYB
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1, κ
    • Specificity
    • Human MYB (Center)
    • Species Reactivity
    • Human
    • Applications
    • WB
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Protein G affinity purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • PBS, pH 7.3.
    • Preservative
    • 0.09% Sodium Azide
    • Storage
    • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been tested for use in Western Blot (1:1000).

    Target

    • Alternative Names
    • Cmyb; efg; c-myb; c-myb_CDS
    • Cellular Localization
    • Nucleus
    • Post Translation Modifications
    • Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
      Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.
      Phosphorylated by HIPK1. This phosphorylation reduces MYB transcription factor activity but not MYB protein levels.
    • Function
    • Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

    Recommended Products

    Secondary Antibody

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "MYB"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Rabbit Monoclonal Antibody Products
    CAT Product Name Application Type
    MOB-2314z Mouse Anti-MYB Recombinant Antibody (clone 40A5) WB, FC, ICC, IF, IP Mouse IgG1
    ZG-0477U Rabbit Anti-Phospho-MYB (S11) Recombinant Antibody (clone 3F4) ELISA, IF Rabbit IgG
    VS3-QX796 Mouse Anti-MYB Recombinant Antibody (clone 1279CT309.289.119) WB Mouse IgG1
    VS3-CJ556 Rabbit Anti-MYB (phospho S11) Recombinant Antibody (VS3-CJ556) WB, ICC, IF, IHC, FC Rabbit IgG
    VS3-WK2052 Rabbit Anti-MYB (pS11) Recombinant Antibody (clone R11-7D-7) WB, IHC-P, ICC, IF, IP Rabbit IgG

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