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MYB
Loading...Anti-MYB Products
- Mouse Anti-MYB Recombinant Antibody (VS3-CJ555) (VS3-CJ555)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB
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- Mouse Anti-MYB Recombinant Antibody (clone 40A5) (MOB-2314z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IP
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-P, WB
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- Anti-MYB Immunohistochemistry Kit (VS-0525-XY4604)
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- Species Reactivity: Human
- Target: MYB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.
Protein class
Cancer-related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Undifferentiated cells, Breast glandular cells, Respiratory ciliated cells, Intestinal goblet cells, Ionocytes, granulocytes)
Immune cell specificity
Group enriched (eosinophil, basophil, plasmacytoid DC)
Cell line specificity
Cell line enhanced (HL-60, MOLT-4, NB-4, REH, THP-1, U-937)
Interaction
Binds MYBBP1A. Interacts with HIPK2, MAF and NLK (By similarity). Binds to HIPK1.
Molecular function
Activator, DNA-binding
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