Mouse Anti-NFKBIB Recombinant Antibody (clone 3E4)
CAT#: VS3-WK1598
This antibody is a mouse recombinant antibody against human NFKBIB, which belongs to the NF-kappa-B inhibitor family. The clone 3E4 can be used in WB analysis at a dilution of 1/1000-1/2000 and IHC analysis at a dilution of 1/50-1/200.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63734/1139_C10_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104825-NFKBIB
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Specifications
- Immunogen
- Synthesized peptide derived from human IκB β
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human NFKBIB
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 3E4
- Applications
- IHC-P, WB
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 0.5% BSA, 50% Glycerol
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC-P: 1/50-1/200
WB: 1/1000-1/2000
Target
- Alternative Names
- NFKB Inhibitor Beta; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Beta; Thyroid Receptor-Interacting Protein 9; NF-Kappa-B Inhibitor Beta; TR-Interacting Protein 9; I-Kappa-B-Beta; NF-Kappa-BIB
- Gene ID
- 4793
- UniProt ID
- Q15653
- Long Name
- NFKB Inhibitor Beta
- Sequence Similarities
- Belongs to the NF-kappa-B inhibitor family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
- Protein Refseq
- NP_001230045.1; NP_002494.2
- Function
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
Isotype Control
- CAT
- Product Name
See other products for "NFKBIB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-485MZ | Human Anti-NFKBIB Recombinant Antibody (TAB-485MZ) | Cyt, FC, WB | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-485MZ-S(P) | Human Anti-NFKBIB Recombinant Antibody; scFv Fragment (TAB-485MZ-S(P)) | FC, Confocal microscopy, WB, IP | Human scFv |
| TAB-485MZ-F(E) | Human Anti-NFKBIB Recombinant Antibody; Fab Fragment (TAB-485MZ-F(E)) | FC, Confocal microscopy, WB, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0882CT | Recombinant Mouse anti-Human NFKBIB Monoclonal antibody (EML735) | WB | |
| MRO-0823-CN | Recombinant Rabbit Anti-NFKBIB Monoclonal Antibody (CBACN-303) | WB, IF, IHC, IP | Rabbit IgG |
| VS3-WK988 | Mouse Anti-NFKBIB Recombinant Antibody (clone 1F3) | IHC-P, IF | Mouse IgG |
| VS3-WK990 | Rabbit Anti-NFKBIB Recombinant Antibody (VS3-WK990) | WB, ICC, IHC, IP | Rabbit IgG |
| VS13-YC802 | Rabbit Anti-NFKBIB Recombinant Antibody (VS13-YC802) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2436 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIB Monoclonal Antibody (DS2436AB) | ICC, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1227 | AbPlus™ Anti-NFKBIB Magnetic Beads (VS-0724-YC1227) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4823 | Anti-NFKBIB Immunohistochemistry Kit | IHC |
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