AbPlus™ Anti-NFYA Magnetic Beads (VS-0724-YC744) (CAT#: VS-0724-YC744)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-NFYA specific antibody

• Target
• NFYA

• Immunogen
• Synthetic peptide corresponding to the C-terminus of the human NFYA.

• Target Species
• Human, Mouse, Rat

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]

• Alternative Names
• Nuclear Transcription Factor Y Subunit Alpha; Nuclear Transcription Factor Y Subunit A; Nuclear Transcription Factor Y, Alpha; NF-YA; CCAAT-Binding Transcription Factor Subunit B; CAAT-Box DNA Binding Protein Subunit A; CAAT Box DNA-Binding Protein Subunit A;

• Gene ID
• 4800

• UniProt ID
• P23511

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