Mouse Anti-NPY2R Recombinant Antibody (clone L119/106)
CAT#: VS-0625-FY55
The Mouse IgG2a monoclonal antibody, clone L119/106, broadly targets NPY2R in Human, Mouse, and Rat. Its immunogen is a recombinant human NPY2R fusion protein, with an epitope spanning amino acids 1-51 and 330-381. With an approximate antigen size of 45 kDa, this antibody is applicable in ICC, IHC, and WB, offering versatile detection capabilities for NPY2R.
Specifications
- Immunogen
- A recombinant human NPY2R fusion protein, comprising amino acids 1-51 (extracellular N-terminus) and 330-381 (cytoplasmic C-terminus), expressed in E. coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Species Reactivity
- Human, Mouse, Rat
- Clone
- L119/106
- Applications
- Immunocytochemistry, Immunohistochemistry, Western Blot
- Related Disease
- Temporal Lobe Epilepsy and Peripheral Artery Disease
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >90% as determined by SDS-PAGE
- Molecular Weight
- The predicted antigen size is approximately 45 kDa.
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 10 mM Tris, 50 mM Sodium Chloride, pH 7.125
- Preservative
- 0.065% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Optimal dilutions for assays should be determined by the user.
Target
- Alternative Names
- Neuropeptide Y Receptor Y2; NPY-Y2 Receptor; NPY2-R; Neuropeptide Y Receptor Type 2; Y2 Receptor
- Gene ID
- 4887
- UniProt ID
- P49146
- Long Name
- Neuropeptide Y Receptor Y2
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn11
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site
- Protein Refseq
- NP_000901.1; NP_001357109.1; NP_001362399.1
- Function
- Receptor for neuropeptide Y and peptide YY.
The rank order of affinity of this receptor for pancreatic polypeptides is PYY> NPY> PYY (3-36)> NPY (2-36)> [Ile-31, Gln-34] PP> [Leu-31, Pro-34] NPY> PP, [Pro-34] PYY and NPY free acid.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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