Mouse Anti-NPY2R Recombinant Antibody (clone L119/106)

CAT#: VS-0625-FY55

The Mouse IgG2a monoclonal antibody, clone L119/106, broadly targets NPY2R in Human, Mouse, and Rat. Its immunogen is a recombinant human NPY2R fusion protein, with an epitope spanning amino acids 1-51 and 330-381. With an approximate antigen size of 45 kDa, this antibody is applicable in ICC, IHC, and WB, offering versatile detection capabilities for NPY2R.

Specifications

  • Immunogen
  • A recombinant human NPY2R fusion protein, comprising amino acids 1-51 (extracellular N-terminus) and 330-381 (cytoplasmic C-terminus), expressed in E. coli.
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • L119/106
  • Applications
  • Immunocytochemistry, Immunohistochemistry, Western Blot
  • Related Disease
  • Temporal Lobe Epilepsy and Peripheral Artery Disease

Product Property

  • Purification
  • Purified with Protein A or G affinity chromatography
  • Purity
  • >90% as determined by SDS-PAGE
  • Molecular Weight
  • The predicted antigen size is approximately 45 kDa.
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 10 mM Tris, 50 mM Sodium Chloride, pH 7.125
  • Preservative
  • 0.065% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • Optimal dilutions for assays should be determined by the user.

Target

  • Alternative Names
  • Neuropeptide Y Receptor Y2; NPY-Y2 Receptor; NPY2-R; Neuropeptide Y Receptor Type 2; Y2 Receptor
  • Long Name
  • Neuropeptide Y Receptor Y2
  • Sequence Similarities
  • Belongs to the G-protein coupled receptor 1 family.
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • Glycosylation at Asn11
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 1 site
  • Function
  • Receptor for neuropeptide Y and peptide YY.
    The rank order of affinity of this receptor for pancreatic polypeptides is PYY> NPY> PYY (3-36)> NPY (2-36)> [Ile-31, Gln-34] PP> [Leu-31, Pro-34] NPY> PP, [Pro-34] PYY and NPY free acid.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Protocol & Troubleshooting

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