AbPlus™ Anti-NR2C2 Magnetic Beads (T1014F08)
CAT#: VS-0424-XY204
The AbPlus Anti-NR2C2 Magnetic Beads (T1014F08) is an innovative affinity resin which is bound with anti-NR2C2 specific antibody (T1014F08). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of NR2C2 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows nuclear positivity in glandular cells and cels in the endometrial stroma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_B_4_3_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6313/17445_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177463-NR2C2
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-NR2C2 specific antibody (T1014F08)
- Target
- NR2C2
- Immunogen
- Purified NR2C2 fusion protein
- Target Species
- Human
- Antibody Clone
- T1014F08
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Alternative Names
- TR4; TAK1
- Gene ID
- 7182
- UniProt ID
- P49116
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "NR2C2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1450CT | Recombinant Mouse anti-Human NR2C2 Monoclonal antibody (EML2388) | IHC-P, WB | |
| VS3-XY3453 | Rabbit Anti-NR2C2 Recombinant Antibody (clone R78-4M-2) | WB | Rabbit IgG |
| VS3-FY2824 | Mouse Anti-NR2C2 Recombinant Antibody (VS3-FY2824) | WB | Mouse IgG |
| VS7-0425-WR502 | Mouse Anti-NR2C2 Recombinant Antibody (clone 8F2E8) | FC | Mouse IgG1 |
| VS7-0425-WR503 | Mouse Anti-NR2C2 Recombinant Antibody (clone 8H11D4) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2490 | Hi-Affi™ Recombinant Rabbit Anti-NR2C2 Monoclonal Antibody (DS2490AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-093CN | Human Anti-NR2C2 Recombinant Antibody (clone T1014F08) | WB, ELISA, IHC, IP | Human IgG |
| NS-094CN | Human Anti-NR2C2 Recombinant Antibody (clone T1014G03) | WB, ELISA, IHC, IP | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-093CN-F(E) | Human Anti-NR2C2 Recombinant Antibody (clone T1014F08); Fab Fragment | WB, ELISA, IHC, IP | Human Fab |
| NS-094CN-F(E) | Human Anti-NR2C2 Recombinant Antibody (clone T1014G03); Fab Fragment | WB, ELISA, IHC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-093CN-S(P) | Human Anti-NR2C2 Recombinant Antibody (clone T1014F08); scFv Fragment | WB, ELISA, IHC, IP | Human scFv |
| NS-094CN-S(P) | Human Anti-NR2C2 Recombinant Antibody (clone T1014G03); scFv Fragment | WB, ELISA, IHC, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4951 | Anti-NR2C2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4952 | Anti-Mouse NR2C2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4953 | Anti-Rat NR2C2 Immunohistochemistry Kit | IHC |
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