Mouse Anti-PBRM1 Recombinant Antibody (VS3-FY2830) (CAT#: VS3-FY2830)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Mouse PBRM1

• Species Reactivity
• Human, Mouse

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 192.9 kDa.

• Related Disease
• Renal Cell Carcinoma; Nonpapillary; Clear Cell Papillary Renal Cell Carcinoma

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000

• Alternative Names
• Polybromo 1; BRG1-Associated Factor 180; Polybromo-1D; BAF180; PB1; Protein Polybromo-1; HPB1

• Gene ID
• 55193

• UniProt ID
• Q86U86

• Cellular Localization
• Nucleus

• Post Translation Modifications
• Ubiquitination at Lys754, Lys1398, Lys1626, and Lys1642 (NX_Q86U86 [NX_Q86U86-1])
  Modification sites at PhosphoSitePlus (Q86U86)
  Glycosylation from GlyGen (Q86U86) 3 sites, 1 O-linked glycan (3 sites)

• Protein Refseq
• XP_011532204.1

• Function
• Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
  Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF).
  Acts as a negative regulator of cell proliferation.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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