AibGenesis™ Rabbit Anti-PCBD1 Recombinant Antibody (AibG-Rb-PC635)
CAT#: VS-0426-FY635
This AI-discovered antibody targets PCBD1. It is affinity purified and optimized for WB and IHC, supporting research into amino acid metabolism and transcription.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37575/403_G5_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61723/if_selected.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37575/74189_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37575/74189_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37575/74189_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, Hep G2)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166228-PCBD1
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PCBD1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-PC635
- Applications
- Western Blot, Immunohistochemistry, Immunofluorescence-Paraffin
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Hyperphenylalaninemia
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 150 mM NaCl, 50% Glycerol
- Preservative
- 0.02% New type preservative N
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:1000-1:5000), Immunohistochemistry (1:50-1:100), Immunofluorescence-Paraffin (1:50-1:100)
Target
- Alternative Names
- DCoH; PCBD; PCBD1; PCD; PHS
- Gene ID
- 5092
- UniProt ID
- P61457
- Long Name
- Pterin-4 Alpha-Carbinolamine Dehydratase 1
- Sequence Similarities
- Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Ubiquitination at Lys41 and Lys59 (NX_P61457 [NX_P61457-1])
Modification sites at PhosphoSitePlus (P61457)
- Protein Refseq
- NP_000272.1; NP_001276726.1; NP_001309933.1
- Function
- Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity).
Also acts as a coactivator for HNF1B-dependent transcription (PubMed:24204001).
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PCBD1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1568CT | Recombinant Mouse anti-Human PCBD1 Monoclonal antibody (EML559) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2609 | Hi-Affi™ Recombinant Rabbit Anti-PCBD1 Monoclonal Antibody (DS2609AB) | WB, IHC, ICC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY2179 | Rabbit Anti-PCBD1 Recombinant Antibody (clone R41-2R-5) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1577 | Anti-PCBD1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5228 | Anti-Human PCBD1 Immunohistochemistry Kit | IHC |
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