AbPlus™ Anti-PDX1 Magnetic Beads (VS-0724-YC1106)
CAT#: VS-0724-YC1106
The AbPlus Anti-PDX1 Magnetic Beads (VS-0724-YC1106) is an innovative affinity resin which is bound with anti-PDX1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PDX1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/1645_D3_14_cr57beb44007e74_selected.jpg
Normal Tissue
Figure 2 High expression in duodenum
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_8_2_val_selected.jpg
Normal Tissue
Figure 3 Low expression in prostate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_3_5_val_selected.jpg
Normal Tissue
Figure 4 Colon
Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes -
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_9_3.jpg
Normal Tissue
Figure 5 Pancreas
Exocrine glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_1_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HEK93, HeLa, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139515-PDX1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-PDX1 specific antibody
- Target
- PDX1
- Immunogen
- A synthetic peptide corresponding to the N-terminus of the human PDX1.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
- Alternative Names
- Pancreatic And Duodenal Homeobox 1; Insulin Promoter Factor 1, Homeodomain Transcription Factor; Somatostatin-Transactivating Factor 1; Somatostatin Transcription Factor 1; Insulin Upstream Factor 1; Islet/Duodenum Homeobox-1; Glucose-Sensitive Factor; STF-1; IDX-1; IPF-1; IUF-1;
- Gene ID
- 3651
- UniProt ID
- P52945
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Related Diseases
Type I Diabetes Mellitus
Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PDX1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3868z | Mouse Anti-PDX1 Recombinant Antibody (clone 30D12) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MOB-1331CT | Recombinant Mouse anti-Human PDX1 Monoclonal antibody (3B23) | ICC, IF, IHC-P, WB | |
| MRO-1202-CN | Recombinant Rabbit Anti-PDX1 Monoclonal Antibody (JM62-45) | WB, IHC, IF | Rabbit IgG |
| VS3-QX864 | Mouse Anti-PDX1 Recombinant Antibody (clone 5A5) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-XY1236 | Mouse Anti-PDX1 Recombinant Antibody (clone 2G12) | ELISA, WB, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2652 | Hi-Affi™ Recombinant Rabbit Anti-PDX1 Monoclonal Antibody (DS2652AB) | WB, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY175 | CytoStream™ Mouse Anti-PDX1 Recombinant Antibody (VS-0225-XY175) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5300 | Anti-PDX1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5301 | Anti-Mouse PDX1 Immunohistochemistry Kit | IHC |
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