AbPlus™ Anti-PDX1 Magnetic Beads (VS-0724-YC1106) (CAT#: VS-0724-YC1106)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-PDX1 specific antibody

• Target
• PDX1

• Immunogen
• A synthetic peptide corresponding to the N-terminus of the human PDX1.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

• Alternative Names
• Pancreatic And Duodenal Homeobox 1; Insulin Promoter Factor 1, Homeodomain Transcription Factor; Somatostatin-Transactivating Factor 1; Somatostatin Transcription Factor 1; Insulin Upstream Factor 1; Islet/Duodenum Homeobox-1; Glucose-Sensitive Factor; STF-1; IDX-1; IPF-1; IUF-1;

• Gene ID
• 3651

• UniProt ID
• P52945

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