Disease related genes, Human disease related genes, Transcription factors
Intracellular
Cell type enhanced (Cholangiocytes, Enteroendocrine cells, Ductal cells, Exocrine glandular cells, Gastric mucus-secreting cells)
Not detected in immune cells
Cell line enhanced (HDLM-2, HEK93, HeLa, OE19)
Interacts with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). Interacts with SPOP (By similarity). Interacts with the methyltransferase SETD7. Part of a PDX1:PBX1b:MEIS2b complex.
Activator, Developmental protein, DNA-binding
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For Research Use Only. Not For Clinical Use.