Rabbit Anti-PHOX2B Recombinant Antibody (clone R01-5G9) (CAT#: VS3-XY3464)
This product is a recombinant rabbit antibody that recognizes PHOX2B (Paired like homeobox 2B), which involves in the development of several major noradrenergic neuron populations. This antibody specifically recognizes human PHOX2B. It also has cross-reactivity against mouse PHOX2B. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Specific Inquiry
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse PHOX2B
- Species Reactivity
- Human, Mouse
- Clone
- R01-5G9
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Central Hypoventilation Syndrome, Congenital, 1; Neuroblastoma 2
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- CCHS; PMX2B; NBLST2; NBPhox
- Gene ID
- 8929
- UniProt ID
- Q99453
- Long Name
- Paired like homeobox 2B
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q99453)
Modification sites at neXtProt (NX_Q99453)
- Protein Refseq
- NP_003915.2
- Function
- Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus.
Transcription factor which could determine a neurotransmitter phenotype in vertebrates.
Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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