Rabbit Anti-PHOX2B Recombinant Antibody (clone R01-5G9)
CAT#: VS3-XY3464
This product is a recombinant rabbit antibody that recognizes PHOX2B (Paired like homeobox 2B), which involves in the development of several major noradrenergic neuron populations. This antibody specifically recognizes human PHOX2B. It also has cross-reactivity against mouse PHOX2B. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse PHOX2B
- Species Reactivity
- Human, Mouse
- Clone
- R01-5G9
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Central Hypoventilation Syndrome, Congenital, 1; Neuroblastoma 2
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- CCHS; PMX2B; NBLST2; NBPhox
- Gene ID
- 8929
- UniProt ID
- Q99453
- Long Name
- Paired like homeobox 2B
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q99453)
Modification sites at neXtProt (NX_Q99453)
- Protein Refseq
- NP_003915.2
- Function
- Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus.
Transcription factor which could determine a neurotransmitter phenotype in vertebrates.
Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
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- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PHOX2B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5379 | Anti-PHOX2B Immunohistochemistry Kit | IHC | |
| VS-0525-XY5380 | Anti-Mouse PHOX2B Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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