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    Mouse Anti-PON1 Monoclonal Antibody (clone 4G8A12) (CAT#: VS7-0425-WR650)

    This product is a mouse IgG1 antibody that binds to human PON1. The antibody 4G8A12 recognizes specific amino acid domain of human PON1 (AA: 20-155). It can be used for WB, IHC, and FC assays.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IHC staining of human liver
    Figure 1 IHC staining of human liver
    (Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/ihc_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Neuronal cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_9_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_4_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Not detected
    Figure 8 RNA cell line category: Not detected
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005421-PON1/subcellular

    Specifications

    • Immunogen
    • Recombinant human PON1 (AA: 20-155) fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human PON1
    • Species Reactivity
    • Human
    • Clone
    • 4G8A12
    • Molecule Class
    • Paraoxonase Family
    • Applications
    • WB, IHC, FC
    • Conjugate
    • Unconjugated
    • Related Disease
    • Microvascular complications of diabetes 5 (MVCD5)

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Preservative
    • 0.03% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry-Paraffin: 1:200 - 1:1000
      Flow Cytometry: 1:200 - 1:400
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • PON1; MVCD5; PON; Paraoxonase 1; Serum Aryldialkylphosphatase 1; Paraoxonase B-Type; Arylesterase 1; EC 3.1.8.1; Arylesterase B-Type; K-45; Serum Aryldiakylphosphatase; Aromatic Esterase 1; EC 3.1.1.81; Serum Paraoxonase/Arylesterase 1
    • Long Name
    • Serum paraoxonase and arylesterase 1
    • Cellular Localization
    • HDL; Secreted
    • Post Translation Modifications
    • Disulfide bond; Glycoprotein
    • Function
    • Hydrolase

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "PON1"

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    CAT Product Name Application Type
    MOB-1710z Mouse Anti-PON1 Recombinant Antibody (clone 22G10) WB, ELISA, FC, IHC Mouse IgG1
    MOB-2409CT Recombinant Mouse anti-Human PON1 Monoclonal antibody (FQ3048BZ) ICC, IF, IHC-FoFr, ELISA, WB, FC
    VS3-XY1276 Mouse Anti-PON1 Recombinant Antibody (clone 4G8D3) IHC, ICC Mouse IgG1
    VS3-XY1277 Mouse Anti-PON1 Recombinant Antibody (clone 3D3) ELISA, WB, FC, IHC Mouse IgG1
    VS3-FY1840 Rabbit Anti-PON1 Recombinant Antibody (clone R07-4I1) WB, IP Rabbit IgG

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