Mouse Anti-PON1 Monoclonal Antibody (clone 4G8A12) (CAT#: VS7-0425-WR650)
This product is a mouse IgG1 antibody that binds to human PON1. The antibody 4G8A12 recognizes specific amino acid domain of human PON1 (AA: 20-155). It can be used for WB, IHC, and FC assays.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/ihc_selected.jpg

(Neuronal cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_B_8_5.jpg

(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_9_3.jpg

(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_7_4.jpg

(Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_5.jpg

(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_4_6.jpg

(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005421-PON1/subcellular
Specifications
- Immunogen
- Recombinant human PON1 (AA: 20-155) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PON1
- Species Reactivity
- Human
- Clone
- 4G8A12
- Molecule Class
- Paraoxonase Family
- Applications
- WB, IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Microvascular complications of diabetes 5 (MVCD5)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- PON1; MVCD5; PON; Paraoxonase 1; Serum Aryldialkylphosphatase 1; Paraoxonase B-Type; Arylesterase 1; EC 3.1.8.1; Arylesterase B-Type; K-45; Serum Aryldiakylphosphatase; Aromatic Esterase 1; EC 3.1.1.81; Serum Paraoxonase/Arylesterase 1
- Gene ID
- 5444
- UniProt ID
- P27169
- Long Name
- Serum paraoxonase and arylesterase 1
- Cellular Localization
- HDL; Secreted
- Post Translation Modifications
- Disulfide bond; Glycoprotein
- Protein Refseq
- NP_000437.3
- Function
- Hydrolase
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PON1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1710z | Mouse Anti-PON1 Recombinant Antibody (clone 22G10) | WB, ELISA, FC, IHC | Mouse IgG1 |
MOB-2409CT | Recombinant Mouse anti-Human PON1 Monoclonal antibody (FQ3048BZ) | ICC, IF, IHC-FoFr, ELISA, WB, FC | |
VS3-XY1276 | Mouse Anti-PON1 Recombinant Antibody (clone 4G8D3) | IHC, ICC | Mouse IgG1 |
VS3-XY1277 | Mouse Anti-PON1 Recombinant Antibody (clone 3D3) | ELISA, WB, FC, IHC | Mouse IgG1 |
VS3-FY1840 | Rabbit Anti-PON1 Recombinant Antibody (clone R07-4I1) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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