Rabbit Anti-RAB25 Recombinant Antibody (VS13-YC967)

CAT#: VS13-YC967

The Rabbit Anti-RAB25 Recombinant Antibody is specific for human RAB25. RAB25, involved in membrane trafficking and cell survival, acts as a tumor suppressor or oncogene contextually. The anti-RAB25 antibody can be used for Western blot (1/500-1/1000).

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 High expression in esophagus. Figure 3 Colon Figure 4 Liver Figure 5 Kidney Figure 6 RNA cell line category: Cell line enhanced (BEWO, CAPAN-2, MCF7, OE19, RT4, SK-BR-3, T-47d)

Specifications

  • Immunogen
  • Recombinant human Rab25.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human RAB25
  • Species Reactivity
  • Human
  • Conjugate
  • NONE

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
  • Preservative
  • 0.02% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000

Target

  • Alternative Names
  • RAB25, Member RAS Oncogene Family; CATX-8; Ras-Related Protein Rab-25; RAB11C; CATX8;
  • Long Name
  • RAB25, member RAS oncogene family
  • Sequence Similarities
  • Belongs to the small GTPase superfamily. Rab family.
  • Cellular Localization
  • Cell membrane; Cell projection; Cytoplasmic vesicle; Membrane
  • Function
  • Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226).
    Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity).
    May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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