Rabbit Anti-RAPGEF3 Recombinant Antibody (VS13-YC979) (CAT#: VS13-YC979)
The Rabbit Anti-RAPGEF3 Recombinant Antibody is specific for human and mouse RAPGEF3. RAPGEF3 encodes a guanine nucleotide exchange factor affecting pathways like platelet cytosolic Ca2+ response, linked to diseases like asthma. The anti-RAPGEF3 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry-paraffin (1/50-1/200), Immunoprecipitation (1/10-1/50), Immunocytochemistry (1/10-1/50), Immunofluorescence (1/10-1/50).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4386/672_D11_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4386/672_D11_2_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43518/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43518/ihc_selected.jpg
Figure 3 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of reaction center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4386/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of reaction center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4386/ihc_selected.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40365/103989_A_5_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40365/103989_A_5_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, NB-4, RPTEC TERT1, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079337-RAPGEF3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079337-RAPGEF3
Specifications
- Immunogen
- Recombinant human Epac1, aa 874-923.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse RAPGEF3
- Species Reactivity
- Human, Mouse
- Applications
- WB, IHC-P, IP, ICC, IF
- Conjugate
- NONE
- Related Disease
- Thrombocytopenia, Cyclic and Asthma
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Immunoprecipitation (IP): 1/10-1/50
Immunocytochemistry (ICC): 1/10-1/50
Immunofluorescence (IF): 1/10-1/50
Target
- Alternative Names
- Rap Guanine Nucleotide Exchange Factor 3; Exchange Protein Directly Activated By CAMP 1; Rap1 Guanine-Nucleotide-Exchange Factor Directly Activated By CAMP; CAMP-Regulated Guanine Nucleotide Exchange Factor I; Rap Guanine Nucleotide Exchange Factor (GEF) 3; Exchange Factor Directly Activated By CAMP 1; CAMP-GEFI; EPAC 1;
- Gene ID
- 10411
- UniProt ID
- O95398
- Long Name
- Rap Guanine Nucleotide Exchange Factor 3
- Cellular Localization
- Endomembrane system
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "RAPGEF3"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1390MZ | Recombinant Mouse Anti-Human RAPGEF3 Antibody | ELISA, WB | Mouse antibody |
| MRO-0536-CN | Recombinant Rabbit Anti-RAPGEF3 Monoclonal Antibody (JM63-29) | WB, IHC, IP, IF | Rabbit IgG |
| VS3-XY1359 | Mouse Anti-RAPGEF3 Recombinant Antibody (clone 4G3) | WB, IP, IF, IHC | Mouse IgG1 |
| VS3-FY1249 | Recombinant Rabbit Anti-RAPGEF3 Antibody (clone R05-6B2) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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