Rabbit Anti-RBPJ Recombinant Antibody (VS13-YC993)
CAT#: VS13-YC993
The Rabbit Anti-RBPJ Recombinant Antibody is specific for human RBPJ. RBPJ encodes a transcriptional regulator in the Notch signaling pathway. It acts as a repressor without Notch proteins and as an activator when bound to them, recruiting chromatin remodeling complexes to pathway genes, with several isoforms and pseudogenes on chromosome 9. The anti-RBPJ antibody can be used for Western blot (1/1000-1/5000).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60647/1227_G4_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows strong positivity in neuropil.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/251/1013_B_8_6_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/251/1013_B_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/251/1013_A_4_6.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000168214-RBPJ
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Specifications
- Immunogen
- Recombinant human RBPJK, aa 81-184.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human RBPJ
- Species Reactivity
- Human
- Applications
- WB
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000-1/5000
Target
- Alternative Names
- Recombination Signal Binding Protein For Immunoglobulin Kappa J Region; Renal Carcinoma Antigen NY-REN-30; RBP-J Kappa; IGKJRB1; RBPSUH; IGKJRB; RBP-JK; CBF-1; RBP-J; RBPJK; Immunoglobulin Kappa J Region Recombination Signal Binding Protein 1; Recombining Binding Protein Suppressor Of Hairless (Drosophila);
- Gene ID
- 3516
- UniProt ID
- Q06330
- Long Name
- Recombination Signal Binding Protein For Immunoglobulin Kappa J Region
- Cellular Localization
- Nucleus; Cytoplasm
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "RBPJ"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3404z | Mouse Anti-RBPJ Recombinant Antibody (clone 1B11) | IHC, IF, WB, FC | Mouse IgG1 |
| MOB-1780CT | Recombinant Mouse anti-Human RBPJ Monoclonal antibody (EML477) | WB | |
| MRO-1326-CN | Recombinant Rabbit Anti-RBPJ Monoclonal Antibody (JB49-34) | WB | Rabbit IgG |
| VS3-FY1260 | Recombinant Rabbit Anti-RBPJ Antibody (clone R05-6G4) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3030 | Hi-Affi™ Recombinant Rabbit Anti-RBPJ Monoclonal Antibody (DS3030AB) | WB, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1896 | Anti-RBPJ Immunohistochemistry Kit | IHC | |
| VS-0525-XY6049 | Anti-Human RBPJ Immunohistochemistry Kit | IHC |
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