Recombinant Anti-RETN Eliminating Antibody, pH-Sensitive (VS-0625-YC277)
CAT#: VS-0625-YC277
The anti-RETN eliminating antibody is an engineered pH-sensitive antibody against human RETN. RETN is a hormone potentially linking obesity with type II diabetes. The antibody has a novel RETN-sweeping activity in vivo, which selectively eliminatesthe soluble RETN from plasma. Compared to conventional antibody, the mAb exerted in vivo efficacy by simultaneously engineering both pH-dependent antigen binding, to mimic the pH-dependent receptor-ligand binding of such endocytic receptors, and increased FcRn binding affinity at neutral pH, to mimic the cell-bound form of the receptors.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (NB-4, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104918-RETN
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG1
- Specificity
- Human RETN
- Species Reactivity
- Human
- Applications
- Antigen-Sweeping In Vivo.
Product Property
- Purification
- Protein A/G purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS only
- Preservative
- None
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0625-YC277. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "RETN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2194z | Mouse Anti-RETN Recombinant Antibody (clone 36A12) | WB, ELISA, IHC | Mouse IgG2b, κ |
| MOB-1808CT | Recombinant Mouse anti-Human RETN Monoclonal antibody (4E8-2E22) | ELISA | |
| HPAB-0156-YC | Human Anti-RETN Recombinant Antibody (HPAB-0156-YC) | ELISA, IP, Neut | Humanized IgG1 |
| ZG-457C | Human Anti-RETN Recombinant Antibody (clone 8-F9) | ELISA | Human IgG1, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3053 | Hi-Affi™ Recombinant Rabbit Anti-RETN Monoclonal Antibody (DS3053AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-YC-S(P) | Human Anti-RETN Recombinant Antibody; scFv Fragment (HPAB-0156-YC-S(P)) | ELISA, IP, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-YC-F(E) | Human Anti-RETN Recombinant Antibody; Fab Fragment (HPAB-0156-YC-F(E)) | ELISA, IP, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6084 | Anti-RETN Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, IHC, FC, IP, IF, FuncS
-3.jpg)
Application: Neut
Application: ELISA, FC, Neut, Inhib
-2.png)
Application: ELISA
Application: ELISA, Vaccine, FuncS
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
