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RETN
Loading...Anti-RETN ProductsBackground
Anti-RETN Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IHC
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- Human Anti-RETN Recombinant Antibody (HPAB-0156-YC) (HPAB-0156-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, IP, Neut
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- Human Anti-RETN Recombinant Antibody; scFv Fragment (HPAB-0156-YC-S(P)) (HPAB-0156-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, IP, Neut
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- Human Anti-RETN Recombinant Antibody; Fab Fragment (HPAB-0156-YC-F(E)) (HPAB-0156-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, IP, Neut
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Anti-RETN Immunohistochemistry Kit (VS-0525-XY6084)
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- Species Reactivity: Human
- Target: RETN
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Protein class
Candidate cardiovascular disease genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Group enriched (Hofbauer cells, Macrophages, monocytes, Kupffer cells)
Immune cell specificity
Group enriched (classical monocyte, myeloid DC, intermediate monocyte, non-classical monocyte)
Cell line specificity
Group enriched (NB-4, U-937)
Interaction
Homodimer; disulfide-linked (By similarity). Interacts with DEFA1 (PubMed:15064728).
Molecular function
Hormone
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