Mouse Anti-RUNX1 Recombinant Antibody (clone 6C12B3) (CAT#: VS7-0425-WR804)
This product is a mouse IgG1 antibody that binds to human RUNX1. The antibody 6C12B3 recognizes specific amino acid domain of human RUNX1 (AA: 237-337). It can be used for WB and ELISA assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
Figure 2 High expression in breast
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (HEL, HMC-1, JURKAT)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
Specifications
- Immunogen
- Recombinant human RUNX1 (AA: 237-337) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human RUNX1
- Species Reactivity
- Human
- Clone
- 6C12B3
- Molecule Class
- Runt-Related Domain-Containing Family
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Familial platelet disorder with associated myeloid malignancy (FPDMM)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- RUNX1; PEA2-Alpha B; AML1-EVI-1 Fusion Protein; CBF-Alpha-2; EVI-1; Runt-Related Transcription Factor 1; Aml1 Oncogene; PEBP2aB; Oncogene AML-1; PEBP2-Alpha B; Acute Myeloid Leukemia 1 Protein; AML1-EVI-1; SL3-3 Enhancer Factor 1 Alpha B Subunit; AMLCR1;
- Gene ID
- 861
- UniProt ID
- Q01196
- Long Name
- Runt Related Transcription Factor 1
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Acetylation; Methylation; Phosphoprotein
- Protein Refseq
- NP_001001890.1
- Function
- Activator; DNA-binding; Repressor
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RUNX1"
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Rabbit Monoclonal Antibody Products
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3142 | Hi-Affi™ Recombinant Rabbit Anti-RUNX1 Monoclonal Antibody (DS3142AB) | WB, IHC-P | IgG |
| MOR-4728 | Hi-Affi™ Recombinant Rabbit Anti-RUNX1 Monoclonal Antibody (TH242DS) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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