Mouse Anti-Serpinh1 Recombinant Antibody (VS3-FY2870) (CAT#: VS3-FY2870)
This anti-Serpinh1 antibody is a mouse recombinant monoclonal antibody. It has been specifically designed to target the human, mouse Serpinh1 protein, a calculated molecular weight of the protein is about 46.5 kDa. This monoclonal antibody proves valuable in disease research related to Osteogenesis Imperfecta, Type X and Preterm Premature Rupture of The Membranes. The antibody can be utilized for detection of Serpinh1 by Western Blot (1/500-1/2000), Immunohistochemistry (1/50-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/1866_A1_36_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/1866_A1_36_selected.jpg
Figure 2 IHC staining of human vulva/anal skin
(Immunohistochemical staining of human vulva/anal skin shows moderate cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/63002_B_6_8_selected.jpg
(Immunohistochemical staining of human vulva/anal skin shows moderate cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/63002_B_6_8_selected.jpg
Figure 3 IHC staining of human breast
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/ihc_selected.jpg
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_B_9_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_8_3.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_9_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_9_5.jpg
Figure 7 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_6_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (CACO-2, fHDF/TERT166, HHSteC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149257-SERPINH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149257-SERPINH1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse Serpinh1
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 46.5 kDa.
- Related Disease
- Osteogenesis Imperfecta, Type X; Preterm Premature Rupture of The Membranes
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Target
- Alternative Names
- Serpin Family H Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Cell Proliferation-Inducing Gene 14 Protein; Rheumatoid Arthritis-Related Antigen RA-A47; Arsenic-Transactivated Protein 3; Collagen Binding Protein 1; 47 KDa Heat Shock Protein; SERPINH2; AsTP3; HSP47; CBP1; CBP2; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 2, (Collagen-Binding Protein 2)
- Gene ID
- 871
- UniProt ID
- P50454
- Cellular Localization
- Endoplasmic reticulum lumen
- Post Translation Modifications
- Glycosylation at Asn120 and Asn125 (NX_P50454 [NX_P50454-1])
Ubiquitination at Lys39, Lys94, Lys319, and Lys380 (NX_P50454 [NX_P50454-1])
Modification sites at PhosphoSitePlus (P50454)
Glycosylation from GlyConnect SERPH_HUMAN (658)
Glycosylation from GlyGen (P50454) 6 sites, 28 N-linked glycans (2 sites), 1 O-linked glycan (4 sites)
- Protein Refseq
- XP_024304524.1
- Function
- Binds specifically to collagen.
Could be involved as a chaperone in the biosynthetic pathway of collagen.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "SERPINH1"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2872z | Mouse Anti-SERPINH1 Recombinant Antibody (clone 1B4) | WB, ICC, IF | Mouse IgG1, κ |
| MOB-0879CT | Recombinant Mouse anti-Human SERPINH1 Monoclonal antibody (EML235) | ICC/IF, IHC-P, WB | |
| MRO-1943-CN | Rabbit Anti-SERPINH1 Polyclonal Antibody (MRO-1943-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0559U | Rabbit Anti-SERPINH1 Recombinant Antibody (clone 10B2) | ELISA, IHC | Rabbit IgG |
| VS3-XY3501 | Rabbit Anti-SERPINH1 Recombinant Antibody (clone R09-6D6) | WB, IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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