Mouse Anti-Serpinh1 Recombinant Antibody (VS3-FY2870) (CAT#: VS3-FY2870)
This anti-Serpinh1 antibody is a mouse recombinant monoclonal antibody. It has been specifically designed to target the human, mouse Serpinh1 protein, a calculated molecular weight of the protein is about 46.5 kDa. This monoclonal antibody proves valuable in disease research related to Osteogenesis Imperfecta, Type X and Preterm Premature Rupture of The Membranes. The antibody can be utilized for detection of Serpinh1 by Western Blot (1/500-1/2000), Immunohistochemistry (1/50-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/1866_A1_36_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/1866_A1_36_selected.jpg
Figure 2 IHC staining of human vulva/anal skin
(Immunohistochemical staining of human vulva/anal skin shows moderate cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/63002_B_6_8_selected.jpg
(Immunohistochemical staining of human vulva/anal skin shows moderate cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29198/63002_B_6_8_selected.jpg
Figure 3 IHC staining of human breast
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/ihc_selected.jpg
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_B_9_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_8_3.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_9_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_9_5.jpg
Figure 7 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4441/11576_A_6_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (CACO-2, fHDF/TERT166, HHSteC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149257-SERPINH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149257-SERPINH1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse Serpinh1
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 46.5 kDa.
- Related Disease
- Osteogenesis Imperfecta, Type X; Preterm Premature Rupture of The Membranes
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Target
- Alternative Names
- Serpin Family H Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Cell Proliferation-Inducing Gene 14 Protein; Rheumatoid Arthritis-Related Antigen RA-A47; Arsenic-Transactivated Protein 3; Collagen Binding Protein 1; 47 KDa Heat Shock Protein; SERPINH2; AsTP3; HSP47; CBP1; CBP2; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 2, (Collagen-Binding Protein 2)
- Gene ID
- 871
- UniProt ID
- P50454
- Cellular Localization
- Endoplasmic reticulum lumen
- Post Translation Modifications
- Glycosylation at Asn120 and Asn125 (NX_P50454 [NX_P50454-1])
Ubiquitination at Lys39, Lys94, Lys319, and Lys380 (NX_P50454 [NX_P50454-1])
Modification sites at PhosphoSitePlus (P50454)
Glycosylation from GlyConnect SERPH_HUMAN (658)
Glycosylation from GlyGen (P50454) 6 sites, 28 N-linked glycans (2 sites), 1 O-linked glycan (4 sites)
- Protein Refseq
- XP_024304524.1
- Function
- Binds specifically to collagen.
Could be involved as a chaperone in the biosynthetic pathway of collagen.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Rabbit Monoclonal Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2872z | Mouse Anti-SERPINH1 Recombinant Antibody (clone 1B4) | WB, ICC, IF | Mouse IgG1, κ |
| MOB-0879CT | Recombinant Mouse anti-Human SERPINH1 Monoclonal antibody (EML235) | ICC, IF, IHC-P, WB | |
| MRO-1943-CN | Rabbit Anti-SERPINH1 Polyclonal Antibody (MRO-1943-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0559U | Rabbit Anti-SERPINH1 Recombinant Antibody (clone 10B2) | ELISA, IHC | Rabbit IgG |
| VS3-XY3501 | Rabbit Anti-SERPINH1 Recombinant Antibody (clone R09-6D6) | WB, IHC-P | Rabbit IgG |
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