AbPlus™ Anti-SGK1 Magnetic Beads (VS-0724-YC419)
CAT#: VS-0724-YC419
The AbPlus Anti-SGK1 Magnetic Beads (VS-0724-YC419) is an innovative affinity resin which is bound with anti-SGK1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SGK1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear speckles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51251/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic and nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25148/56215_A_2_1_selected.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/49011_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HHSteC, RPTEC TERT1, SK-MEL-30, TIME, U-266/84)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118515-SGK1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SGK1 specific antibody
- Target
- SGK1
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human SGK1/SGK.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
- Alternative Names
- Serum/Glucocorticoid Regulated Kinase 1; EC 2.7.11.1; SGK; Serum/Glucocorticoid-Regulated Kinase 1; Serum/Glucocorticoid Regulated Kinase; Serine/Threonine-Protein Kinase Sgk1; Serine/Threonine Protein Kinase SGK; Sgk1 Variant I3; EC 2.7.11;
- Gene ID
- 6446
- UniProt ID
- O00141
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Related Signaling Pathways
mTOR Signaling Pathway
Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "SGK1"
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|---|---|---|---|
| IAB-B057(A) | Recombinant Anti-human SGK1 Intrabody [(D-Arg)9] | WB, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B057(G) | Recombinant Anti-human SGK1 Intrabody [+36 GFP] | WB, ICC, Neut, FuncS | scFv-(+36GFP) |
| IAB-B057(T) | Recombinant Anti-human SGK1 Intrabody [Tat] | PCA, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1839MZ | Recombinant Mouse Anti-Human SGK1 Antibody | ICC, IF, IHC-P, WB | Mouse antibody |
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| VS3-QX1007 | Mouse Anti-SGK1 Recombinant Antibody (clone 6E4-8G5-6D10) | IHC | Mouse IgG1 |
| VS4-CJ113 | Recombinant Mouse Anti-SGK1 Antibody (VS4-CJ113) | ELISA, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0530MZ | Chicken Anti-SGK (ab1) Polyclonal IgY | WB | Chicken antibody |
| BRD-0531MZ | Chicken Anti-SGK (ab2) Polyclonal IgY | WB | Chicken antibody |
| BRD-0761MZ | Chicken Anti-SGK1 Polyclonal IgY | ELISA, IHC, IP, WB | Chicken antibody |
| BRD-1049MZ | Chicken Anti-SGK1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3249 | Hi-Affi™ Recombinant Rabbit Anti-SGK1 Monoclonal Antibody (DS3249AB) | WB, FC, IP, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2059 | Anti-SGK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6541 | Anti-Mouse SGK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6540 | Anti-Human SGK1 Immunohistochemistry Kit | IHC |
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