AbPlus™ Anti-SGK1 Magnetic Beads (VS-0724-YC419) (CAT#: VS-0724-YC419)
The AbPlus Anti-SGK1 Magnetic Beads (VS-0724-YC419) is an innovative affinity resin which is bound with anti-SGK1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SGK1 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51251/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51251/if_selected.jpg

Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/if_selected.jpg

Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic and nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25148/56215_A_2_1_selected.jpg
(Immunohistochemical staining of human stomach shows strong cytoplasmic and nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25148/56215_A_2_1_selected.jpg

Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/49011_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22085/49011_A_6_6.jpg

Figure 5 RNA cell line category: Cell line enhanced (HHSteC, RPTEC TERT1, SK-MEL-30, TIME, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118515-SGK1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118515-SGK1
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SGK1 specific antibody
- Target
- SGK1
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human SGK1/SGK.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
- Alternative Names
- Serum/Glucocorticoid Regulated Kinase 1; EC 2.7.11.1; SGK; Serum/Glucocorticoid-Regulated Kinase 1; Serum/Glucocorticoid Regulated Kinase; Serine/Threonine-Protein Kinase Sgk1; Serine/Threonine Protein Kinase SGK; Sgk1 Variant I3; EC 2.7.11;
- Gene ID
- 6446
- UniProt ID
- O00141
Related Resources
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B057(A) | Recombinant Anti-human SGK1 Intrabody [(D-Arg)9] | WB, Neut, FuncS | scFv-(D-Arg)9 |
IAB-B057(G) | Recombinant Anti-human SGK1 Intrabody [+36 GFP] | WB, ICC, Neut, FuncS | scFv-(+36GFP) |
IAB-B057(T) | Recombinant Anti-human SGK1 Intrabody [Tat] | PCA, Neut, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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