Human Anti-SLC40A1 Recombinant Antibody (clone L2.2-4); Fab Fragment
CAT#: HPAB-0753-CN-F(E)
This is an humanized recombinant antibody L2.2-4 that binds to and inhibits human FPN1. Mab L2.2-4 is effective in maintaining the transport of iron out of mammalian cells and increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and hematocrit in a subject in vivo.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65634/1249_G12_3_selected.jpg
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human
- Species Reactivity
- Cynomolgus monkey
- Clone
- L2.2-4
- Applications
- ELISA
- Related Disease
- Anemia of chronic disease, anemia of cancer, anemia of inflammation
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Solute Carrier Family 40 Member 1; Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 3; Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1; SLC11A3; IREG1; FPN1; Iron-Regulated Transporter 1; Iron Regulated Gene 1;
- Gene ID
- 30061
- UniProt ID
- Q9NP59
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone L2.2-4"
- CAT
- Product Name
See other products for "SLC40A1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-576CL | Human Anti-SLC40A1 Recombinant Antibody (TAB-576CL) | ELISA | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-044WM | Mouse Anti-SLC40A1 Recombinant Antibody (TAB-044WM) | IF, WB, ELISA, IHC | Mouse IgG |
| TAB-044WM-S(P) | Mouse Anti-SLC40A1 Recombinant Antibody; scFv Fragment (TAB-044WM-S(P)) | ELISA, IHC, WB | Mouse scFv |
| TAB-044WM-F(E) | Mouse Anti-SLC40A1 Recombinant Antibody; Fab Fragment (TAB-044WM-F(E)) | ELISA, IHC, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-045WM | Human Anti-SLC40A1 Recombinant Antibody (TAB-045WM) | ELISA, WB | Human IgG |
| TAB-045WM-S(P) | Human Anti-SLC40A1 Recombinant Antibody; scFv Fragment (TAB-045WM-S(P)) | ELISA, WB | Human scFv |
| TAB-045WM-F(E) | Human Anti-SLC40A1 Recombinant Antibody; Fab Fragment (TAB-045WM-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750-CN | Mouse Anti-SLC40A1 Recombinant Antibody (clone 34A9) | ELISA | Mouse IgG |
| HPAB-0752-CN | Human Anti-SLC40A1 Recombinant Antibody (clone 4A10-3) | ELISA | Humanized IgG4 |
| HPAB-0753-CN | Human Anti-SLC40A1 Recombinant Antibody (clone L2.2-4) | ELISA | Humanized IgG4 |
| HPAB-AP801-YC | Human Anti-SLC40A1 Recombinant Antibody (clone 3D8) | Inhib | Human IgG |
| HPAB-AP802-YC | Human Anti-SLC40A1 Recombinant Antibody (HPAB-AP802-YC) | ELISA, Inhib, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750-CN-S(P) | Mouse Anti-SLC40A1 Recombinant Antibody (clone 34A9); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0752-CN-S(P) | Human Anti-SLC40A1 Recombinant Antibody (clone 4A10-3); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0753-CN-S(P) | Human Anti-SLC40A1 Recombinant Antibody (clone L2.2-4); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0754-CN-S(P) | Human Anti-SLC40A1 Recombinant Antibody (clone Com11GY); scFv Fragment | ELISA | Humanized scFv |
| HPAB-AP801-YC-S(P) | Human Anti-SLC40A1 Recombinant Antibody (clone 3D8); scFv Fragment | Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750-CN-F(E) | Mouse Anti-SLC40A1 Recombinant Antibody (clone 34A9); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0752-CN-F(E) | Human Anti-SLC40A1 Recombinant Antibody (clone 4A10-3); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0754-CN-F(E) | Human Anti-SLC40A1 Recombinant Antibody (clone Com11GY); Fab Fragment | ELISA | Humanized Fab |
| HPAB-AP801-YC-F(E) | Human Anti-SLC40A1 Recombinant Antibody (clone 3D8); Fab Fragment | Inhib | Human Fab |
| HPAB-AP802-YC-F(E) | Human Anti-SLC40A1 Recombinant Antibody; Fab Fragment (HPAB-AP802-YC-F(E)) | ELISA, Inhib, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC335 | Recombinant Anti-SLC40A1 Vesicular Antibody, EV Displayed (VS-0425-YC335) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6683 | Anti-SLC40A1 Immunohistochemistry Kit | IHC |
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