Human Anti-sLea Recombinant Antibody (HPAB-0067-WJ)
CAT#: HPAB-0067-WJ
This product is a human monoclonal IgG1 antibody targeting carbohydrate antigen sialyl-Lewis(a) (sLea/CA19.9) through p-isothiocyanatobenzyl-desferrioxamine (DFO-Bz-NCS).
Specifications
- Host Species
- Human
- Derivation
- Hybridoma
- Type
- Human IgG1
- Specificity
- Human sLea
- Species Reactivity
- Human
- Applications
- ELISA, FC, Inhib, IRMA, Cyt, IHC, IF
- Related Disease
- Cancers
Applications
- Application Notes
- The sLea antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Inhibition, Immunoradiometric Assay, Cytotoxicity, Immunohistochemistry, Immunofluorescence.
Target
- Alternative Names
- sLea; Human sLea
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Reliable Tool for Immunohistochemistry
In our IHC assays, this sLea antibody offers clear and distinct staining of cancer tissue samples. It has become an invaluable tool for visualizing sLea expression, crucial for understanding tumor biology and progression, supported by Creative Biolabs' excellent customer service.
Versatile Applications in Cancer Research
The versatility of the sLea antibody in ELISA and flow cytometry applications has broadened our research capabilities. Its consistency and specificity help deliver high-quality, reliable data necessary for meticulous cancer research pursuits.
Robust Performance in Flow Cytometry
This antibody delivers robust performance in flow cytometry applications, essential for analyzing cell surface carbohydrates in tumors. The precise binding to sLea ensures clear and interpretable results, facilitating deeper insights into cancer progression.
Q&As
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What does the sLea antibody target in research?
A: The Human Anti-sLea Recombinant Antibody targets the sialyl-Lewis(a) antigen, a carbohydrate structure significant in mediating cell adhesion processes. It is frequently used in cancer research, particularly for studying metastasis, due to its role in tumor cell adhesion to endothelial cells.
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What is the specificity of this antibody?
A: This human IgG1 antibody specifically binds to the sLea/CA19.9 carbohydrate antigen, known for its expression on various adenocarcinomas, including pancreatic, gastric, and colorectal cancers, thus aiding in detailed cancer biomarker research.
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What applications are recommended for using this antibody?
A: The antibody is suitable for ELISA, Flow Cytometry (FC), Inhibition, Immunoradiometric Assay (IRMA), Cytotoxicity assays, Immunohistochemistry (IHC), and Immunofluorescence (IF). These applications are critical in exploring the expression and function of sLea in cancer biology.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# HPAB-0067-WJ, RRID: AB_3111351)
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "sLea"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0067-WJ-S(P) | Human Anti-sLea Recombinant Antibody scFv Fragment (HPAB-0067-WJ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0067-WJ-F(E) | Human Anti-sLea Recombinant Antibody Fab Fragment (HPAB-0067-WJ-F(E)) | ELISA, FC | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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