Rabbit Anti-SPTA1 Recombinant Antibody (clone R09-7X1) (CAT#: VS3-XY3512)
This product is a recombinant rabbit antibody binding to SPTA1 (Spectrin alpha, erythrocytic 1), which is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. The antibody specifically recognizes the epitope of human SPTA1. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28048/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28048/ihc_selected.jpg
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic positivity in red blood cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28253/ihc_selected.jpg
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic positivity in red blood cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28253/ihc_selected.jpg
Figure 3 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37246/85443_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37246/85443_A_6_6.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37246/85443_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37246/85443_A_7_4.jpg
Figure 5 RNA cell line category: Cell line enriched (K-562)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163554-SPTA1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163554-SPTA1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human SPTA1
- Species Reactivity
- Human
- Clone
- R09-7X1
- Applications
- WB, IHC-P
- Related Disease
- Elliptocytosis 2; Pyropoikilocytosis, Hereditary
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- EL2; HPP; HS3; SPH3; SPTA
- Gene ID
- 6708
- UniProt ID
- P02549
- Long Name
- Spectrin alpha, erythrocytic 1
- Cellular Localization
- Cytoplasm, cytoskeleton
- Post Translation Modifications
- Glycosylation at Ser844, Ser1250, and Ser1737 (NX_P02549 [NX_P02549-1])
Ubiquitination at Lys1803 (NX_P02549 [NX_P02549-1])
Modification sites at PhosphoSitePlus (P02549)
Glycosylation from GlyConnect SPTA1_HUMAN (2880)
Glycosylation from GlyGen (P02549) 4 sites, 1 O-linked glycan (4 sites)
- Protein Refseq
- XP_011508219.1; XP_011508218.1
- Function
- Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane.
It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "SPTA1"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0586MZ | Recombinant Mouse Anti-Human SPTA1 Antibody (clone BG20) | ICC, IP, WB | Mouse antibody |
| VS2-QX78 | Mouse Anti-SPTA1 Recombinant Antibody (clone BRIC 172) | FuncS | Mouse IgG1, κ |
| VS2-QX79 | Mouse Anti-SPTA1 Recombinant Antibody (clone BRIC 276) | FuncS | Mouse IgG1, κ |
| VS13-YC1108 | Rabbit Anti-SPTA1 Recombinant Antibody (VS13-YC1108) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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